Selp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Selp
selectin, platelet
MGI:98280

31 phenotypes from 4 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Selp^tm1.1Rpmc/Selp^tm1.1Rpmc B6.129S1-Selp^tm1.1Rpmc	impaired leukocyte tethering or rolling	J:230041
Selp^tm1Bay/Selp^tm1Bay B6.129S7-Selp^tm1Bay	decreased mast cell number	J:121083
Selp^tm1Bay/Selp^tm1Bay B6.129S7-Selp^tm1Bay	decreased susceptibility to type IV hypersensitivity reaction	J:121083
Selp^tm1Bay/Selp^tm1Bay B6.129S7-Selp^tm1Bay/J	abnormal T cell physiology	J:113536
Selp^tm1Bay/Selp^tm1Bay D1.129S7(B6J)-Selp^tm1Bay	abnormal cytokine secretion	J:57086
	increased IgG level	J:57086
	increased susceptibility to induced arthritis	J:57086
Selp^tm1Bay/Selp^tm1Bay either: B6.129S7-Selp^tm1Bay or (involves: 129S7/SvEvBrd * C57BL/6)	abnormal leukocyte tethering or rolling	J:31374
	increased leukocyte cell number	J:31374
Selp^tm1Bay/Selp^tm1Bay involves: 129S7/SvEvBrd * C57BL/6	increased neutrophil cell number	J:112286
Selp^tm1Bay/Selp^tm1Bay involves: 129S7/SvEvBrd * C57BL/6J	abnormal leukocyte migration	J:24239
	abnormal pilomotor reflex	J:101979
	abnormal spleen morphology	J:101979
	decreased locomotor activity	J:101979
	eye inflammation	J:101979
	head tilt	J:101979
	hepatic necrosis	J:101979
	increased leukocyte cell number	J:101979
	increased neutrophil cell number	J:24239, J:101979
	increased susceptibility to bacterial infection	J:101979
	spinning	J:101979
	tremors	J:101979
	weight loss	J:101979
Selp^tm1Hyn/Selp^tm1Hyn involves: 129S2/SvPas	impaired leukocyte tethering or rolling	J:29814
	impaired macrophage chemotaxis	J:29814
	increased neutrophil cell number	J:29814
Selp^tm1Hyn/Selp^tm1Hyn involves: 129S2/SvPas * C57BL/6	impaired eosinophil recruitment	J:57973
	impaired leukocyte tethering or rolling	J:57973
	impaired neutrophil recruitment	J:57973
	increased eosinophil cell number	J:57973
	increased neutrophil cell number	J:57973
Selp^tm1Hyn/Selp^tm1Hyn involves: 129S2/SvPas * C57BL/6J	impaired leukocyte tethering or rolling	J:77329
	impaired neutrophil recruitment	J:77329
	increased bleeding time	J:31431
	increased neutrophil cell number	J:77329
	skin hemorrhage	J:31431
Selp^tm2Hyn/Selp^tm2Hyn involves: 129S2/SvPas * C57BL/6J	abnormal blood coagulation	J:125020
	abnormal blood homeostasis	J:51068, J:125020
	abnormal vascular endothelial cell morphology	J:51068
	hemorrhage	J:125020
	impaired leukocyte tethering or rolling	J:51068
	impaired neutrophil recruitment	J:51068

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24