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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Scg5
secretogranin V
MGI:98289
55 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Scg5em1(IMPC)Mbp/Scg5em1(IMPC)Mbp
C57BL/6NCrl-Scg5em1(IMPC)Mbp/MbpMmucd 		abnormal behavior J:211773
abnormal retina vasculature morphology J:211773
abnormal spleen morphology J:211773
decreased anxiety-related response J:211773
decreased thigmotaxis J:211773
enlarged spleen J:211773
hyperactivity J:211773
increased circulating alkaline phosphatase level J:211773
increased lean body mass J:211773
increased mean corpuscular volume J:211773
increased monocyte cell number J:211773
Scg5tm1Led/Scg5tm1Led
either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * FVB) or (involves: 129S6/SvEvTac * C57BL/6) 		abnormal adipose tissue distribution J:53349, J:77510
abnormal adrenal gland morphology J:53349
abnormal cardiovascular system morphology J:77510
abnormal circulating insulin level J:53349
abnormal gland morphology J:53349
abnormal glucose homeostasis J:77510
abnormal hair growth J:77510
abnormal mineral level J:77510
abnormal pancreatic islet morphology J:53349
abnormal respiration J:77510
adrenal cortical hyperplasia J:53349
alopecia J:77510
bruising J:53349
convulsive seizures J:77510
cryptorchism J:77510
decreased body size J:53349
decreased body temperature J:77510
decreased circulating glucagon level J:53349
decreased circulating magnesium level J:77510
dystrophic cardiac calcinosis J:77510
ecchymosis J:53349
enlarged heart J:77510
enlarged liver J:77510
hemorrhage J:53349
hemothorax J:53349
hepatic necrosis J:77510
hepatic steatosis J:53349, J:77510
hyperkeratosis J:53349
hypoglycemia J:53349
increased adrenocorticotropin level J:53349
increased circulating corticosterone level J:53349
increased circulating lactate level J:77510
increased liver glycogen level J:77510
increased pancreatic beta cell mass J:53349
pallor J:53349
pancreatic islet hyperplasia J:53349
polyphagia J:77510
postnatal lethality, incomplete penetrance J:53349
respiratory distress J:77510
small adenohypophysis J:77510
sparse hair J:77510
spleen atrophy J:53349
thin dermal layer J:53349
thin skin J:53349
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory