Sst Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sst
somatostatin
MGI:98326

29 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sst^{tm1(cre/ERT2)Zjh}/Sst⁺ involves: C57BL/6 * SJL	no abnormal phenotype detected	J:151755
Sst^{tm1b(KOMP)Wtsi}/Sst^{tm1b(KOMP)Wtsi} C57BL/6N-Sst^{tm1b(KOMP)Wtsi}/Rbrc	decreased bone mineral content	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased lean body mass	J:211773
	increased circulating iron level	J:211773
	increased circulating serum albumin level	J:211773
	increased total body fat amount	J:211773
Sst^tm1Low/Sst^tm1Low B6.129P2-Sst^tm1Low	abnormal circulating pituitary hormone level	J:70016
	abnormal excitatory postsynaptic potential	J:108920
	abnormal inhibitory postsynaptic potential	J:108920
	abnormal nervous system electrophysiology	J:108920
	decreased growth hormone level	J:70016
	normal immune system phenotype	J:126384
	increased circulating gastrin level	J:126384
	increased susceptibility to age related obesity	J:70016
Sst^tm1Ute/Sst^tm1Ute 129-Sst^tm1Ute/J	abnormal motor learning	J:70426
	normal behavior/neurological phenotype	J:70426
	normal homeostasis/metabolism phenotype	J:70426
	increased circulating corticosterone level	J:70426
	increased circulating growth hormone level	J:70426
	normal nervous system phenotype	J:70426
Sst^tm1Ute/Sst^tm1Ute involves: 129S4/SvJae * C57BL/6	abnormal gastric gland morphology	J:97527
	abnormal gastric parietal cell morphology	J:97527
	abnormal stomach fundus morphology	J:97527
	enlarged stomach	J:97527
	hyperchlorhydria	J:97527
Sst^tm1Ute/Sst^tm1Ute involves: 129S4/SvJae * C57BL/6J	decreased circulating prolactin level	J:179095
	normal homeostasis/metabolism phenotype	J:179095
	increased circulating ghrelin level	J:179095
	increased circulating insulin level	J:179095
Sst^{tm2.1(cre)Zjh}/Sst^{tm2.1(cre)Zjh} involves: 129S4/SvJae * C57BL/6 * SJL	no abnormal phenotype detected	J:151755
Sst^{tm3.1(flpo)Zjh}/Sst^{tm3.1(flpo)Zjh} involves: 129S4/SvJae * BALB/cJ * C57BL/6	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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