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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Snai1
snail family zinc finger 1
MGI:98330
65 phenotypes from 7 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm4(Snai1)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA 		abnormal embryo development J:194078
embryonic lethality during organogenesis, complete penetrance J:194078
Meox2tm1(cre)Sor/Meox2+
Snai1tm1Grid/Snai1tm2Grid
involves: 129S1/Sv * 129S4/SvJaeSor 		abnormal allantois morphology J:111702
abnormal cardiac outflow tract development J:111702
abnormal direction of embryo turning J:111702
abnormal direction of heart looping J:111702
abnormal fetal atrioventricular canal morphology J:111702
abnormal heart development J:111702
abnormal primitive streak morphology J:111702
embryonic lethality during organogenesis, complete penetrance J:111702
increased allantois apoptosis J:111702
Snai1tm1.1Stjw/Snai1+
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal cell migration J:146645
abnormal cell physiology J:146645
Snai1tm1.1Stjw/Snai1tm1.1Stjw
Commd10Tg(Vav1-icre)A2Kio/Commd10+
B6.Cg-Snai1tm1.1Stjw Commd10Tg(Vav1-icre)A2Kio 		no abnormal phenotype detected J:214991
Snai1tm1.1Stjw/Snai1tm1.1Stjw
Tg(Tek-cre)1Ywa/0
B6.Cg-Snai1tm1.1Stjw Tg(Tek-cre)1Ywa 		abnormal angiogenesis J:214991
abnormal brain vasculature morphology J:214991
abnormal developmental vascular remodeling J:214991
abnormal placental labyrinth vasculature morphology J:214991
abnormal vascular branching morphogenesis J:214991
abnormal vitelline vascular remodeling J:214991
decreased angiogenesis J:214991
decreased atrioventricular cushion size J:214991
decreased embryo size J:214991
embryonic lethality during organogenesis, complete penetrance J:214991
thin placenta labyrinth J:214991
Snai1tm1.1Stjw/Snai1tm1.1Stjw
Twist2tm1.1(cre)Dor/Twist2+
B6.129(SJL)-Twist2tm1.1(cre)Dor Snai1tm1.1Stjw 		no abnormal phenotype detected J:214991
Snai1tm1Grid/Snai1tm1Grid
Not Specified 		abnormal gastrulation J:72861
abnormal mesoderm development J:72861
absent amnion J:72861
absent chorion J:72861
decreased embryo size J:72861
embryonic growth retardation J:72861
embryonic lethality between somite formation and embryo turning, complete penetrance J:72861
Snai1tm1Grid/Snai1tm2.1Grid
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J 		abnormal mesoderm development J:105294
Snai1tm1Grid/Snai1tm2Grid
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * C57BL/6 * CBA 		no abnormal phenotype detected J:121243
Snai1tm2.1Grid/Snai1tm2.1Grid
involves: 129S1/Sv * C57BL/6J 		abnormal mesoderm development J:105294
embryonic growth arrest J:105294
embryonic lethality, complete penetrance J:105294
Tg(KRT14-Snai1)1Efu/0
involves: CD-1 		abnormal epidermal layer morphology J:97750
abnormal epidermal-dermal junction morphology J:97750
abnormal sebocyte differentiation J:229072
cachexia J:97750
decreased body size J:97750
decreased food intake J:97750
decreased sensitivity to induced cell death J:229072
flaky skin J:97750
increased basal cell carcinoma incidence J:229072
increased keratinocyte proliferation J:229072
increased metastatic potential J:229072
increased sebaceous gland tumor incidence J:229072
increased skin squamous cell carcinoma incidence J:229072
increased skin tumor incidence J:229072
sebaceous gland hyperplasia J:229072
short tail J:97750
thick epidermis J:97750
Tg(Myh6-Snai1)B10Jcc/0
Not Specified 		abnormal heart echocardiography feature J:126850
abnormal impulse conducting system conduction J:126850
abnormal myocardial fiber physiology J:126850
abnormal myocardial fiber sodium currents J:126850
decreased cardiac muscle contractility J:126850
dilated cardiomyopathy J:126850
dilated heart left ventricle J:126850
normal mortality/aging J:126850
prolonged PR interval J:126850
prolonged QRS complex duration J:126850
Tg(Myh6-Snai1)B10Jcc/Tg(Myh6-Snai1)B10Jcc
Not Specified 		abnormal impulse conducting system conduction J:126850
ascites J:126850
cachexia J:126850
congestive heart failure J:126850
decreased cardiac muscle contractility J:126850
decreased heart left ventricle wall thickness J:126850
dilated cardiomyopathy J:126850
dilated heart ventricle J:126850
enlarged heart J:126850
premature death J:126850
prolonged PR interval J:126850
prolonged QRS complex duration J:126850
thin ventricular wall J:126850
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory