Son Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Son
Son DNA binding protein
MGI:98353

46 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Son^{em1(IMPC)Wtsi}/Son^{em1(IMPC)Wtsi} C57BL/6N-Son^{em1(IMPC)Wtsi}/Wtsi	increased mean corpuscular hemoglobin	J:211773
Son^em1.1Bcgen/Son⁺ B6(Cg)-Son^em1.1Bcgen	abnormal B cell differentiation	J:347709
	abnormal bone marrow cell morphology/development	J:347709
	abnormal bone marrow hematopoietic cell morphology	J:347709
	abnormal erythropoiesis	J:347709
	abnormal fetal liver hematopoietic progenitor cell morphology	J:347709
	abnormal kidney morphology	J:347709
	abnormal naive B cell morphology	J:347709
	abnormal response to novel object	J:347709
	abnormal transitional stage B cell morphology	J:347709
	decreased body length	J:347709
	decreased bone marrow cell number	J:347709
	decreased bone trabecula number	J:347709
	decreased erythroid progenitor cell number	J:347709
	decreased femoral compact bone area	J:347709
	decreased follicular B cell number	J:347709
	decreased hematopoietic stem cell number	J:347709
	decreased IgA level	J:347709
	decreased IgM level	J:347709
	decreased leukocyte cell number	J:347709
	decreased lymphocyte cell number	J:347709
	decreased monocyte cell number	J:347709
	decreased neutrophil cell number	J:347709
	decreased trabecular bone volume	J:347709
	decreased transitional stage T2 B cell number	J:347709
	hyperactivity	J:347709
	impaired hematopoiesis	J:347709
	impaired spatial working memory	J:347709
	increased bone trabecular spacing	J:347709
	increased marginal zone B cell number	J:347709
	increased mean corpuscular volume	J:347709
	increased megakaryocyte-erythroid progenitor cell number	J:347709
	increased pre-B cell number	J:347709
	increased thigmotaxis	J:347709
	increased transitional stage T1 B cell number	J:347709
	kyphoscoliosis	J:347709
	macrocytosis	J:347709
	microcephaly	J:347709
	postnatal growth retardation	J:347709
	premature death	J:347709
	prenatal lethality, incomplete penetrance	J:347709
	renal hypoplasia	J:347709
	single kidney	J:347709
	slow postnatal weight gain	J:347709
	thrombocytopenia	J:347709
Son^em1.1Bcgen/Son^em1.1Bcgen B6(Cg)-Son^em1.1Bcgen	embryonic lethality prior to organogenesis, complete penetrance	J:347709

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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