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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Son
Son DNA binding protein
MGI:98353
46 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sonem1(IMPC)Wtsi/Sonem1(IMPC)Wtsi
C57BL/6N-Sonem1(IMPC)Wtsi/Wtsi 		increased mean corpuscular hemoglobin J:211773
Sonem1.1Bcgen/Son+
B6(Cg)-Sonem1.1Bcgen 		abnormal B cell differentiation J:347709
abnormal bone marrow cell morphology/development J:347709
abnormal bone marrow hematopoietic cell morphology J:347709
abnormal erythropoiesis J:347709
abnormal fetal liver hematopoietic progenitor cell morphology J:347709
abnormal kidney morphology J:347709
abnormal naive B cell morphology J:347709
abnormal response to novel object J:347709
abnormal transitional stage B cell morphology J:347709
decreased body length J:347709
decreased bone marrow cell number J:347709
decreased bone trabecula number J:347709
decreased erythroid progenitor cell number J:347709
decreased femoral compact bone area J:347709
decreased follicular B cell number J:347709
decreased hematopoietic stem cell number J:347709
decreased IgA level J:347709
decreased IgM level J:347709
decreased leukocyte cell number J:347709
decreased lymphocyte cell number J:347709
decreased monocyte cell number J:347709
decreased neutrophil cell number J:347709
decreased trabecular bone volume J:347709
decreased transitional stage T2 B cell number J:347709
hyperactivity J:347709
impaired hematopoiesis J:347709
impaired spatial working memory J:347709
increased bone trabecular spacing J:347709
increased marginal zone B cell number J:347709
increased mean corpuscular volume J:347709
increased megakaryocyte-erythroid progenitor cell number J:347709
increased pre-B cell number J:347709
increased thigmotaxis J:347709
increased transitional stage T1 B cell number J:347709
kyphoscoliosis J:347709
macrocytosis J:347709
microcephaly J:347709
postnatal growth retardation J:347709
premature death J:347709
prenatal lethality, incomplete penetrance J:347709
renal hypoplasia J:347709
single kidney J:347709
slow postnatal weight gain J:347709
thrombocytopenia J:347709
Sonem1.1Bcgen/Sonem1.1Bcgen
B6(Cg)-Sonem1.1Bcgen 		embryonic lethality prior to organogenesis, complete penetrance J:347709
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory