Sox10 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sox10
SRY (sex determining region Y)-box 10
MGI:98358

40 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Sox10^tm1Weg/Sox10⁺ Tg(Tyr-NRASQ61K)1Bee/0 involves: 129S1/Sv 129X1/SvJ * C57BL/6J * DBA/2 * SJL	normal neoplasm	J:193443
	normal pigmentation phenotype	J:193443
Erbb3^msp1/Erbb3^msp1 Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	embryonic lethality during organogenesis, incomplete penetrance	J:138775
	hypopigmentation	J:138775
	lethality throughout fetal growth and development, incomplete penetrance	J:138775
	preweaning lethality, complete penetrance	J:138775
Gli3^Mos1/Gli3⁺ Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	belly spot	J:136642
	belted	J:136642
	hypopigmentation	J:136642
Gli3^Xt-J/Gli3⁺ Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ	belly spot	J:136642
	belted	J:136642
	hypopigmentation	J:136642
Gutl1^C3HeB/FeJ/Gutl1^C3HeB/FeJ Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	abnormal intestine morphology	J:117027
Hprt1^{tm1(tetO-Runx1,-EGFP)Enk}/Hprt1⁺ Sox10^tm2(rtTA)Weg/Sox10⁺ involves: 129P2/OlaHsd	abnormal skin pigmentation	J:165939
	decreased birth body size	J:165939
	hyperresponsive to tactile stimuli	J:165939
	megacolon	J:165939
	postnatal lethality, complete penetrance	J:165939
	small dorsal root ganglion	J:165939
Mos3/Mos3⁺ Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/c	hypopigmentation	J:136642
msp4/msp4 Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	hypopigmentation	J:138775
	preweaning lethality, incomplete penetrance	J:138775
mwfh^C3HeB/FeJLe/mwfh^C3HeB/FeJLe Sox10^Dom/? involves: C3HeB/FeJLe * C57BL/6JLe	hypopigmentation	J:53978
Rps7^Zma/Rps7⁺ Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/c * C3H/HeH	abnormal melanoblast morphology	J:195156
	belly spot	J:195156
	decreased body size	J:195156
	hypopigmentation	J:195156
	kinked tail	J:195156
Smarca4^mos6/Smarca4⁺ Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	abnormal melanoblast morphology	J:241206
	belly spot	J:241206
	head spot	J:241206
Smarcc1^msp3/Smarcc1^msp3 Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	hypopigmentation	J:138775
	open neural tube	J:138775
	preweaning lethality, complete penetrance	J:138775
Sox10^df10R/Sox10⁺ involves: 129X1/SvJ * C57BL/6J	belly spot	J:102039
Sox10^tm1Ngan/Sox10⁺ Sox9^tm2Crm/Sox9⁺ Tg(Rr141-cre)1Ksec/0 involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * CBA	dilated cochlea	J:332093
Sox10^tm1Ngan/Sox10⁺ Sox9^tm1.1Ksec/Sox9⁺ Tg(Rr141-cre)1Ksec/0 involves: 129S/SvEv * C57BL/6 * CBA	dilated cochlea	J:332093
Sox10^tm1Weg/Sox10⁺ Tg(Tyr-NRASQ61K)1Bee/0 involves: 129S1/Sv 129X1/SvJ * C57BL/6J * DBA/2	normal pigmentation phenotype	J:193443
Sox10^tm1Weg/Sox10⁺ Tg(Sox10)#Sout/0 involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6 * SJL	normal digestive/alimentary phenotype	J:296651
	normal integument phenotype	J:296651
	normal pigmentation phenotype	J:296651
Sox10^tm5Weg/Sox10⁺ involves: 129P2/OlaHsd * C3H	no abnormal phenotype detected	J:124679
Sox10^tm5Weg/Sox10^tm5Weg involves: 129P2/OlaHsd * C3H	abnormal enteric neuron morphology	J:124679
	abnormal melanoblast migration	J:124679
	abnormal Schwann cell morphology	J:124679
	decreased oligodendrocyte number	J:124679
	dorsal root ganglion hypoplasia	J:124679
	neonatal lethality, incomplete penetrance	J:124679
	normal nervous system phenotype	J:124679
Sox10^{tm6(Sox100B)Weg}/Sox10^{tm6(Sox100B)Weg} involves: 129P2/OlaHsd * C3H	abnormal adrenal medulla morphology	J:160023
	abnormal dorsal root ganglion morphology	J:160023
	abnormal enteric nervous system morphology	J:160023
	abnormal melanoblast morphology	J:160023
	abnormal sympathetic ganglion morphology	J:160023
	abnormal sympathetic neuron morphology	J:160023
	decreased neuron number	J:160023
	dorsal root ganglion hypoplasia	J:160023
	neonatal lethality, complete penetrance	J:160023
	normal nervous system phenotype	J:160023
Sox10^{tm7.1(Sox10)Weg}/Sox10⁺ Tg(Tyr-cre/ERT2)13Bos/0 Tg(Tyr-NRASQ61K)1Bee/0 involves: 129P2/OlaHsd C57BL/6J * DBA/2 * FVB/N	normal pigmentation phenotype	J:193443
Sox10m2^C3HeB/FeJ/Sox10m2^C3HeB/FeJ Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	abnormal intestine morphology	J:117027
Sox10m2^C3HeB/FeJ/Sox10m2^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	abnormal intestine morphology	J:117027
	aganglionic megacolon	J:118320
Sox10m2^C57BL/6J/Sox10m2^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Sox10m3^C3HeB/FeJ/Sox10m3^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Sox10m3^C57BL/6J/Sox10m3^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Sox10m4^C3HeB/FeJ/Sox10m4^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Sox10m4^C57BL/6J/Sox10m4^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Sox10m5^C3HeB/FeJ/Sox10m5^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Sox10m5^C57BL/6J/Sox10m5^C57BL/6J Sox10^Dom/Sox10^Dom involves: C3HeB/FeJ * C57BL/6J	aganglionic megacolon	J:118320
Traf4^m1Pav/Traf4^m1Pav Sox10^tm1Weg/Sox10⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	hypopigmentation	J:138775
	preweaning lethality, incomplete penetrance	J:138775

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