Sox7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sox7
SRY (sex determining region Y)-box 7
MGI:98369

21 phenotypes from 3 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sox7^tm1.1Dsco/Sox7⁺ B6.129-Sox7^tm1.1Dsco	normal muscle phenotype	J:187416
Sox7^tm1.1Dsco/Sox7⁺ involves: 129/Sv * 129S/SvEv * C57BL/6 * C57BL/6J	normal cardiovascular system phenotype	J:338879
	lethality during fetal growth through weaning, incomplete penetrance	J:338879
Sox7^tm1.1Dsco/Sox7⁺ involves: 129S/SvEv * C57BL/6	abnormal diaphragm morphology	J:187416
	abnormal gallbladder morphology	J:187416
	diaphragmatic hernia	J:187416
Sox7^tm1.1Dsco/Sox7^tm1.1Dsco involves: 129S/SvEv * C57BL/6	abnormal atrioventricular cushion morphology	J:338879
	abnormal cardiac epithelial to mesenchymal transition	J:338879
	abnormal fetal atrioventricular canal morphology	J:338879
	abnormal vitelline vascular remodeling	J:187416
	embryonic growth retardation	J:187416
	embryonic lethality during organogenesis, incomplete penetrance	J:187416
	pericardial edema	J:187416
Sox7^tm1.1Nat/Sox7^tm1.1Nat Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal cardiac epithelial to mesenchymal transition	J:306193
	abnormal interventricular septum morphology	J:306193
	atrial septal defect	J:306193
	atrioventricular cushion hypoplasia	J:306193
	normal embryo phenotype	J:306193
	normal mortality/aging	J:306193
	partial atrioventricular septal defect	J:306193
Sox7^tm1.1Nat/Sox7^tm1.1Nat Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ involves: 129 * 129S1/Sv * C57BL/6 * SJL	abnormal cardiac epithelial to mesenchymal transition	J:306193
	atrioventricular cushion hypoplasia	J:306193
Sox7^tm1.1Nat/Sox7^tm1.1Nat Tg(Tek-cre)1Ywa/0 involves: 129 * C57BL/6 * SJL	abnormal vitelline vascular remodeling	J:306193
	embryonic growth retardation	J:306193
Sox7^tm1Dsco/Sox7^tm1.1Dsco Tg(Tek-cre)1Ywa/0 involves: 129S/SvEv * C57BL/6 * SJL	prenatal lethality, complete penetrance	J:338879
	ventricular septal defect	J:338879
Sox7^tm1Dsco/Sox7^tm1Dsco Tg(Tek-cre)1Ywa/0 involves: 129S/SvEv * C57BL/6 * SJL	atrioventricular cushion hypoplasia	J:338879
	prenatal lethality, complete penetrance	J:338879
	ventricular septal defect	J:338879

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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