About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sptb
spectrin beta, erythrocytic
MGI:98387
65 phenotypes from 3 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Sptbem1(IMPC)J/Sptb+
C57BL/6NJ-Sptbem1(IMPC)J/Mmjax 		decreased exploration in new environment J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
increased erythrocyte cell number J:211773
Sptbem1(IMPC)J/Sptbem1(IMPC)J
C57BL/6NJ-Sptbem1(IMPC)J/Mmjax 		abnormal morula morphology J:279207
embryonic lethality before implantation, complete penetrance J:279207
embryonic lethality prior to organogenesis J:211773
failure of blastocyst to hatch from the zona pellucida J:279207
failure of embryo implantation J:279207
preweaning lethality, complete penetrance J:211773
Sptbja/Sptb+
129/Sv-Sptbja 		anemia J:5985
increased erythrocyte protoporphyrin level J:5985
Sptbja/Sptb+
(WB.129-Sptbja/J x B6.129-Sptbja/J)F1 		increased erythrocyte clearance J:44313
increased erythrocyte osmotic fragility J:44313
Sptbja/Sptb+
involves: 129/Sv * C57BL/6J * WB/Re 		increased erythrocyte protoporphyrin level J:5985
Sptbja/Sptbja
129/Sv-Sptbja 		abnormal reticulocyte morphology J:7501
anisocytosis J:305
enlarged heart J:305
enlarged liver J:305
enlarged spleen J:305
hemolytic anemia J:305
jaundice J:305
multifocal hepatic necrosis J:305
neonatal lethality, incomplete penetrance J:7501
poikilocytosis J:305
prenatal lethality, incomplete penetrance J:305
reticulocytosis J:305
Sptbja/Sptbja
(WB.129-Sptbja/J x B6.129-Sptbja/J)F1 		abnormal cardiac thrombosis J:44313, J:62355
abnormal erythrocyte morphology J:62355
abnormal erythrocyte osmotic lysis J:162532
abnormal erythrocyte physiology J:162532
abnormal myocardium layer morphology J:44313
anisopoikilocytosis J:162532
brain lesion J:44313
cardiac hypertrophy J:162532
cerebral infarct J:44313
decreased body size J:162532
decreased brain size J:44313
decreased cellular hemoglobin content J:44313
decreased circulating glucose level J:44313
decreased erythrocyte cell number J:44313
decreased hematocrit J:44313, J:162532
decreased hemoglobin content J:44313, J:162532
decreased total body fat amount J:44313
enlarged heart J:44313
enlarged liver J:44313, J:162532
enlarged spleen J:44313, J:162532
extramedullary hematopoiesis J:162532
glomerulonephritis J:44313
hemolysis J:162532
hemolytic anemia J:162532
hydronephrosis J:44313
increased blood urea nitrogen level J:44313
increased circulating bilirubin level J:44313, J:162532
increased circulating iron level J:44313
increased erythrocyte clearance J:162532
increased kidney iron level J:44313
increased nucleated erythrocyte cell number J:162532
increased spleen red pulp amount J:44313
infertility J:162532
jaundice J:162532
low mean erythrocyte cell number J:162532
microcytosis J:62355
neonatal lethality, incomplete penetrance J:162532
poikilocytosis J:162532
postnatal lethality, incomplete penetrance J:44313, J:162532
premature death J:44313
renal tubular necrosis J:44313
reticulocytosis J:44313, J:162532
schistocytosis J:162532
tubular nephritis J:44313
urolithiasis J:44313
Sptbja/Sptbja
involves: 129/Sv * C57BL/6J * WB/Re 		increased erythrocyte protoporphyrin level J:5985
Sptbm1Jus/Sptbm1Jus
involves: 129S6/SvEvTac * C57BL/6 		abnormal erythrocyte morphology J:159750
acanthocytosis J:159750
anemia J:159750
enlarged heart J:159750
enlarged kidney J:159750
enlarged liver J:159750
enlarged spleen J:159750
hemolysis J:159750
spherocytosis J:159750
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory