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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		T
brachyury, T-box transcription factor T
MGI:98472
76 phenotypes from 29 alleles in 23 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(Actb-T,-GFP)Dalco/Gt(ROSA)26Sortm1(Actb-T,-GFP)Dalco
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:101977
T1Or/T1Or
involves: 101 * C3H 		embryonic growth arrest J:5621
embryonic lethality during organogenesis, complete penetrance J:5621
T2Or/T2Or
involves: 101 * C3H 		embryonic growth arrest J:5621
embryonic lethality during organogenesis, complete penetrance J:5621
T3Or/T3Or
involves: 101 * C3H 		embryonic growth arrest J:5621
embryonic lethality during organogenesis, complete penetrance J:5621
T4J/T+
involves: BALB/cBy 		short tail J:30778
T5J/T+
C57BL/6J-T5J/J 		short tail J:78379
T5Or/T5Or
involves: 101 * C3H 		embryonic growth arrest J:5621
embryonic lethality during organogenesis, complete penetrance J:5621
T6J/T+
involves: A/J * C57BL/6J 		short tail J:78380
T6Or/T6Or
involves: 101 * C3H 		embryonic growth arrest J:5621
embryonic lethality during organogenesis, complete penetrance J:5621
T7J/T+
C57BL/6J-T7J 		short tail J:44446
T7J/T7J
involves: 129S2/SvPas * C57BL/6J 		embryonic lethality between implantation and somite formation, complete penetrance J:44446
T8J/T+
C57BL/6J-Apoetm1Unc 		short tail J:72464
T8J/T8J
C57BL/6J-Apoetm1Unc 		prenatal lethality, complete penetrance J:72464
T9J/T+
C57BL/6J-T9J 		short tail J:72463
T9J/T9J
C57BL/6J-T9J 		prenatal lethality, complete penetrance J:72463
T11J/T+
C57BL/6J-T11J/GrsrJ 		abnormal pelvic girdle bone morphology J:187215
abnormal tail development J:187215
absent anus J:187215
kinked tail J:187215
short tail J:187215
T24H/T+
involves: 101/H * C3H/HeH 		short tail J:169366
T26H/T+
involves: 101/H * C3H/HeH 		absent tail J:169366
T29H/T+
involves: BALB/c * TFH 		perinatal lethality, incomplete penetrance J:62655
T33H/T+
involves: 101/H * C3H/HeH * TFH 		perinatal lethality, incomplete penetrance J:62655
reduced male fertility J:62655
T34H/T+
involves: STOCK T34H * TFH 		edema J:62655
perinatal lethality, incomplete penetrance J:62655
short tail J:62655
T39H/T+
involves: BALB/c * C3H/HeN 		abnormal tail morphology J:63816
T40H/T+
involves: C3H/HeH * C57BL/6J 		short tail J:93195
T40H/T40H
involves: C3H/HeH * C57BL/6J 		absent notochord J:93195
T41H/T+
involves: 101/Rl * BALB/cOlaHsd * C3H/Rl 		short tail J:93195
T41H/T41H
involves: 101/Rl * BALB/cOlaHsd * C3H/Rl 		absent notochord J:93195
Tc-2H/T+
involves: 101/H * C3H/HeH 		abnormal tail morphology J:85396
absent tail J:85396
preweaning lethality, incomplete penetrance J:85396
vestigial tail J:85396
Tc-2H/Tc-2H
involves: 101/H * C3H/HeH 		prenatal lethality J:85396
Tc-3H/T+
involves: BALB/cOlaHsd * C3H/HeH 		absent tail J:93195
Tc-3H/Tc-3H
involves: BALB/cOlaHsd * C3H/HeH 		embryonic lethality, complete penetrance J:93195
incomplete somite formation J:93195
open neural tube J:93195
Tc/T+
mixed 		abnormal neural tube morphology J:106412
abnormal spinal cord morphology J:106412
abnormal tail bud morphology J:106412
absent vertebrae J:106412
spina bifida occulta J:106412
split notochord J:106412
Tc/T+
Not Specified 		abnormal bone ossification J:5003
abnormal cervical atlas morphology J:5003
abnormal cervical vertebrae morphology J:5003
abnormal nucleus pulposus morphology J:5003
abnormal odontoid process morphology J:5003
abnormal tail morphology J:5003, J:64262
abnormal vertebral arch development J:5003
absent tail J:5003, J:64262
cervical vertebral fusion J:5003
decreased presacral vertebrae number J:5003
fusion of vertebral arches J:5003
neonatal lethality, incomplete penetrance J:5003
postnatal lethality J:5003
rib fusion J:5003
short ribs J:5003
short tail J:5003, J:64262
thoracic vertebral fusion J:5003
vertebral fusion J:5003
Tc/Tc
mixed 		abnormal limb bud morphology J:106412
abnormal neural tube morphology J:106412
absent somites J:106412
absent tail bud J:106412
caudal body truncation J:106412
embryonic lethality during organogenesis, complete penetrance J:106412
Tc/Tc
Not Specified 		abnormal allantois morphology J:5003
abnormal embryo development J:5003
abnormal limb bud morphology J:5003
abnormal neural fold formation J:5003
abnormal neural tube morphology J:5003
absent forelimb buds J:5003
absent hindlimb buds J:5003
absent somites J:5003
absent tail bud J:5003
caudal body truncation J:5003
distended pericardium J:5003
embryonic lethality during organogenesis, incomplete penetrance J:5003
kinked neural tube J:5003
Th/T+
Not Specified 		short tail J:13072
Th/Th
Not Specified 		abnormal embryo development J:13072
embryonic lethality, complete penetrance J:13072
TJic/T+
Not Specified 		short tail J:14257
TJic/TJic
Not Specified 		decreased litter size J:14257
TM1Shao/T+
involves: C57BL/6J 		curly tail J:166619
short tail J:166619
TM1Shao/TM1Shao
involves: C57BL/6J 		embryonic lethality during organogenesis, complete penetrance J:166619
Ttm1(cre/ERT2)Hssk/T+
involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR 		abnormal tail morphology J:194054
absent tail J:194054
curly tail J:194054
short tail J:194054
Ttm1(cre/ERT2)Hssk/Ttm1(cre/ERT2)Hssk
involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR 		embryonic lethality, complete penetrance J:194054
TWis/T+
involves: A/J 		absent tail J:9032
TWis/T+
Not Specified 		abnormal neural tube morphology J:16412
abnormal rostral-caudal axis patterning J:16412
abnormal sacral vertebrae morphology J:16412
abnormal tail bud morphology J:16412
abnormal vertebral body morphology J:16412
absent notochord J:16412
absent vertebral body J:16412
decreased rib number J:16412
fusion of vertebral arches J:16412
incomplete caudal neuropore closure J:16412
short tail J:16412
thin tail J:16412
TWis/TWis
involves: A/J 		embryonic lethality J:9032
TWis/TWis
Not Specified 		abnormal axial mesoderm morphology J:78124
abnormal mesoderm development J:16412
abnormal notochord morphology J:78124
abnormal posterior primitive streak morphology J:16412
abnormal prechordal plate morphology J:16412
abnormal primitive streak formation J:16412, J:78124
abnormal spinal cord morphology J:16412
absent allantois J:78124
absent primitive node J:16412
absent somites J:16412
embryonic lethality between somite formation and embryo turning, complete penetrance J:16412, J:78124
Gt(ROSA)26Sor/Gt(ROSA)26Sor+
chimera involves: C57BL/6 or (129S6/SvEvTac x C57BL/6NCr)F1 		abnormal tail development J:173434
truncated notochord J:173434
Gt(ROSA)26Sor/Gt(ROSA)26Sor+
chimera involves: C57BL/6 or (129S6/SvEvTac x C57BL/6NCr)F1 		abnormal neural tube morphology J:173434
absent allantois J:173434
absent notochord J:173434
caudal body truncation J:173434
embryonic lethality during organogenesis, complete penetrance J:173434
impaired somite development J:173434
Gt(ROSA)26Sor/Gt(ROSA)26Sor+
chimera involves: C57BL/6 or (129S6/SvEvTac x C57BL/6NCr)F1 		abnormal mesoderm development J:173434
abnormal neural tube morphology J:173434
absent allantois J:173434
absent notochord J:173434
caudal body truncation J:173434
embryonic lethality during organogenesis, complete penetrance J:173434
impaired somite development J:173434
truncated notochord J:173434
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory