About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		T
brachyury, T-box transcription factor T
MGI:98472
72 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
D17Aus9df10J/T7J
involves: 129S4/SvJae * BALB/cJ * C57BL/6 		absent notochord J:81651
embryonic growth arrest J:81651
embryonic lethality during organogenesis, complete penetrance J:81651
failure of initiation of embryo turning J:81651
D17Aus9df12J/T7J
involves: 129S4/SvJae * BALB/cJ * C57BL/6 		absent notochord J:81651
embryonic growth arrest J:81651
embryonic lethality during organogenesis, complete penetrance J:81651
failure of initiation of embryo turning J:81651
D17Aus9df13J/T7J
involves: 129S4/SvJae * BALB/cJ * C57BL/6 		decreased body size J:81651
Itpr3tf/Itpr3+
T/T+
thr4/t+
involves: BTBR 		transmission ratio distortion J:169366
Nox3het/Nox3het
T31H/T+
involves: 101/H * C3H/HeH * TFH 		head tilt J:62655
Nox3het/Nox3het
T33H/T+
involves: 101/H * C3H/HeH * TFH 		head tilt J:62655
Nox3het/Nox3het
T36H/T+
involves: 101/H * C3H/HeH * TFH 		head tilt J:62655
Sp5tm1Rbe/Sp5tm1Rbe
T/T+
involves: 129P2/Ola * C57BL/6J 		abnormal lumbar vertebrae morphology J:65743
abnormal vertebrae morphology J:65743
decreased caudal vertebrae number J:65743
short tail J:65743
T/T+
Not Specified 		abnormal neural tube morphology J:13018
abnormal notochord morphology J:13018, J:15081
decreased caudal vertebrae number J:15081
decreased presacral vertebrae number J:15081
decreased ventral ectodermal ridge size J:15081
short tail J:13018, J:15081
T/T+
Tg(T)118.9Bgh/0
involves: C57BL/6 * CBA 		normal limbs/digits/tail phenotype J:3956
T/T+
tlow2H/t+
Not Specified 		normal limbs/digits/tail phenotype J:183153
T/T+
thr1/t+
Not Specified 		absent tail J:183153
T/T+
thr4/t+
Not Specified 		absent tail J:169366
T/T+
th7m/t+
Not Specified 		absent tail J:34190
T/T+
th7m2/t+
Not Specified 		absent tail J:34190
T/T+
th7m2/t+
Itpr3tf/Itpr3+
involves: BTBR 		normal reproductive system phenotype J:34190
T/T+
thr15/t+
Not Specified 		absent tail J:192386
T/T
involves: BTBR 		abnormal heart looping J:52218
abnormal heart tube morphology J:52218
T/T
Not Specified 		abnormal dorsal aorta morphology J:13018
abnormal epidermal layer morphology J:13018
abnormal forelimb bud morphology J:13018
abnormal head shape J:13018
abnormal limb bud morphology J:11933
abnormal nervous system development J:13018
abnormal neural tube morphology J:11933, J:13018, J:59271
abnormal pericardial cavity morphology J:13018
abnormal placenta development J:11933
abnormal primitive streak formation J:11933
abnormal somite development J:11933, J:13018
absent hindlimb buds J:13018
absent notochord J:13018
bleb J:13018
caudal body truncation J:13018
decreased embryo size J:11933, J:13018
delayed heart development J:13018
embryonic lethality during organogenesis, complete penetrance J:13018
hemopericardium J:13018
hemorrhage J:13018
kinked neural tube J:59271
notochord degeneration J:11933
short tail J:13018
T/t4
Not Specified 		abnormal tail morphology J:36683
absent tail J:36683
transmission ratio distortion J:36683
T/t6
Not Specified 		abnormal notochord morphology J:15081
decreased ventral ectodermal ridge size J:15081
T t+/T+ th17
Not Specified 		no abnormal phenotype detected J:5889
T t+/T+ th45
Not Specified 		absent tail J:7443
T t+/T+ tTu3
Not Specified 		normal limbs/digits/tail phenotype J:6700
T/tAE5
Not Specified 		abnormal tail morphology J:83862
absent tail J:83862
T/tbtm
involves: C57BL/6 * MOL-NIS 		abnormal lumbar vertebrae morphology J:21054
abnormal neural tube morphology J:21054
abnormal notochord morphology J:21054
abnormal rostral-caudal body axis extension J:21054
abnormal spinal cord morphology J:21054
abnormal tail bud morphology J:21054
abnormal tail development J:21054
abnormal thoracic vertebrae morphology J:21054
absent caudal vertebrae J:21054
absent sacral vertebrae J:21054
absent tail J:21054
absent vertebrae J:21054
absent vertebral arch J:21054
absent vertebral body J:21054
meningomyelocele J:21054
notochord degeneration J:21054
split notochord J:21054
T/tbtm
MOL-NIS 		absent tail J:14919
decreased survivor rate J:14919
perinatal lethality, incomplete penetrance J:14919
normal reproductive system phenotype J:14919
T th20/T+ t+
Not Specified 		absent tail J:5889
T/tks1
Not Specified 		absent tail J:8922
transmission ratio distortion J:8922
T ts6/T+ t+
Not Specified 		transmission ratio distortion J:6478
T/tw3
Not Specified 		absent tail J:23652
T/tw73
involves: M. m. musculus 		absent tail J:175677
transmission ratio distortion J:175677
T/twN27
Not Specified 		absent tail J:32745
T/twPas1
involves: BTBR/Nev T * M. m. brevirostris 		absent tail J:6461
transmission ratio distortion J:6461
T/twPas2
involves: M. m. brevirostris 		absent tail J:6461
transmission ratio distortion J:6461
T/twPas3
involves: M. m. domesticus 		absent tail J:6461
transmission ratio distortion J:6461
T2J/T+
C57BL/6J-T2J/J 		short tail J:78474
T4J/t6
involves: BALB/cBy 		absent tail J:30778
T4Or/T4Or
involves: 101 * C3H 		embryonic growth arrest J:5621
embryonic lethality during organogenesis, complete penetrance J:5621
T5J/t6
involves: C57BL/6J 		absent tail J:78379
T22H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH 		male infertility J:62655
T24H/T+
th2/t+
involves: 101/H * C3H/HeH 		absent tail J:169366
T29H/T+
t6/t+
involves: BALB/c * TFH 		transmission ratio distortion J:62655
T29H/T+
tw32/t+
involves: BALB/c * TFH 		transmission ratio distortion J:62655
T30H/T+
t6/t+
involves: 101/H * C3H/HeH * TFH 		transmission ratio distortion J:62655
T30H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH 		male infertility J:62655
T31H/T+
involves: 101/H * C3H/HeH * TFH 		perinatal lethality, incomplete penetrance J:62655
reduced male fertility J:62655
T31H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH 		male infertility J:62655
T32H/T+
t6/t+
involves: 101/H * C3H/HeH * TFH 		transmission ratio distortion J:62655
T32H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH 		transmission ratio distortion J:62655
T32H/T+
th51/t+
involves: 101/H * C3H/HeH * TFH 		transmission ratio distortion J:62655
T33H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH 		reduced male fertility J:62655
transmission ratio distortion J:62655
T34H/T+
tw32/t+
involves: 101/H * C3H/HeH * STOCK T34H * TFH 		transmission ratio distortion J:62655
T36H/T+
involves: 101/H * C3H/HeH * TFH 		perinatal lethality, incomplete penetrance J:62655
reduced male fertility J:62655
short tail J:62655
T36H/T+
t6/t+
involves: 101/H * C3H/HeH * TFH 		transmission ratio distortion J:62655
T36H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH 		postnatal lethality, complete penetrance J:62655
Tc/T+
Tg(T)118.9Bgh/0
involves: C57BL/6 * CBA 		short tail J:3956
Tc/T+
Tg(T)118.9Bgh/Tg(T)118.9Bgh
involves: C57BL/6 * CBA 		abnormal tail morphology J:3956
Tc/T
Not Specified 		embryonic lethality during organogenesis, complete penetrance J:5003
Tc/Tc
tw5/tw5
mixed 		abnormal colon morphology J:106412
abnormal notochord morphology J:106412
abnormal roof plate morphology J:106412
abnormal spinal cord morphology J:106412
abnormal vertebral body development J:106412
abnormal vertebral body morphology J:106412
distended urinary bladder J:106412
hindlimb paralysis J:106412
meningocele J:106412
postnatal lethality J:106412
split notochord J:106412
Tc/th7
Not Specified 		hindlimb paralysis J:5003
postnatal lethality J:5003
spina bifida occulta J:5003
Tc/th51
Tg(T)118.9Bgh/0
involves: C57BL/6 * CBA 		abnormal tail morphology J:3956
Th/t13
Not Specified 		absent tail J:13072
TTg(MT2A-Myc)137Misu/T+
C57BL/6-TTg(MT2A-Myc)137Misu 		kinked tail J:60706
TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
C57BL/6-TTg(MT2A-Myc)137Misu 		abnormal neural tube morphology J:60706
abnormal notochord morphology J:60706
abnormal somite development J:60706
decreased body size J:60706
distended pericardium J:60706
embryonic growth retardation J:60706
embryonic lethality during organogenesis, complete penetrance J:60706
failure of heart looping J:60706
incomplete embryo turning J:60706
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory