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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tacr1
tachykinin receptor 1
MGI:98475
35 phenotypes from 3 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tacr1tm1Nge/Tacr1tm1Nge
involves: 129S4/SvJae 		abnormal humoral immune response J:35529
abnormal nervous system electrophysiology J:106546
Tacr1tm1Nge/Tacr1tm1Nge
involves: 129S4/SvJae * C57BL 		abnormal mast cell physiology J:84660
decreased vascular permeability J:84660
Tacr1tm1Rhn/Tacr1tm1Rhn
129S/SvEv-Tacr1tm1Rhn 		abnormal body temperature homeostasis J:77640
abnormal neuron physiology J:77640
abnormal nociception after inflammation J:61266
abnormal physiological response to xenobiotic J:77640
decreased anxiety-related response J:77640
decreased circulating corticosterone level J:77640
decreased vocalization J:77640
hyporesponsive to tactile stimuli J:61266
impaired behavioral response to xenobiotic J:77640
increased chemical nociceptive threshold J:61266
Tacr1tm1Sph/Tacr1tm1Sph
involves: 129 * C57BL/6 		abnormal nervous system physiology J:106301
Tacr1tm1Sph/Tacr1tm1Sph
involves: 129P2/OlaHsd 		abnormal dopamine level J:171881
abnormal noradrenaline level J:171881
abnormal pain threshold J:127006
hyperactivity J:171881
impaired behavioral response to addictive substance J:171881
impaired behavioral response to morphine J:171881
impaired conditioned place preference behavior J:171881
impaired coordination J:171881
Tacr1tm1Sph/Tacr1tm1Sph
involves: 129P2/OlaHsd * C57BL/6 		abnormal chemical nociception J:46629
abnormal pain threshold J:46629
abnormal pulmonary respiratory rate response J:89428
abnormal respiratory mucosa goblet cell morphology J:105592
abnormal touch/ nociception J:46629
decreased aggression J:46629
decreased inflammatory response J:46629
decreased nerve fiber response intensity J:46629
hyperalgesia J:103700
increased airway responsiveness J:105592
joint inflammation J:103700
Tacr1tm1Sph/Tacr1tm1Sph
involves: 129P2/OlaHsd * C57BL/6 * MF1 		abnormal thermosensation J:106631
increased locomotor activity J:102131
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory