Tap1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
MGI:98483

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
B2m^tm1Jae/B2m^tm1Jae Tap1^tm1Hpl/Tap1^tm1Hpl B6.129-B2m^tm1Jae Tap1^tm1Hpl	abnormal lateral geniculate nucleus morphology	J:66246
	abnormal long-term depression	J:66246
	abnormal miniature excitatory postsynaptic currents	J:120941
	abnormal synapse morphology	J:120941
	abnormal synaptic bouton morphology	J:120941
	abnormal synaptic vesicle number	J:120941
	enhanced long-term potentiation	J:66246
	enlarged lateral ventricles	J:66246
	reduced long-term depression	J:66246
Cd74^tm1Doi/Cd74^tm1Doi Tap1^tm1Arp/Tap1^tm1Arp involves: 129S2/SvPas * C57BL/6	abnormal T cell number	J:113083
Col1a1^{tm1(tetO-Yod1)Hpl}/Col1a1^{tm1(tetO-Yod1)Hpl} Gt(ROSA)26Sor^{tm1(rtTAM2)Jae}/Gt(ROSA)26Sor^{tm1(rtTAM2)Jae} Tap1^tm1Arp/Tap1^tm1Arp involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal professional antigen presenting cell physiology	J:194608
Erap1^tm1Nsha/Erap1^tm1Nsha Tap1^tm1Arp/Tap1^tm1Arp B6.129-Erap1^tm1Nsha Tap1^tm1Arp	abnormal antigen presentation via MHC class I	J:112389
Erap1^tm1Nsha/Erap1^tm1Nsha Tap1^tm1Arp/Tap1^tm1Arp involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/10 * DBA/2	abnormal antigen presentation via MHC class I	J:116606
Msh2^tm1Htr/Msh2^tm1Htr Tap1^tm1Hpl/Tap1^tm1Hpl involves: 129P2/OlaHsd * FVB	increased gastrointestinal tumor incidence	J:45433
	increased lung tumor incidence	J:45433
	increased mammary gland tumor incidence	J:45433
	increased skin tumor incidence	J:45433
	increased tumor incidence	J:45433
	increased uterus tumor incidence	J:45433
Tap1^tm1Arp/Tap1^tm1Arp X/Yaa BXSB.129S2(B6)-Tap1^tm1Arp/Dcr	increased susceptibility to systemic lupus erythematosus	J:179430

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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