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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
MGI:98484
11 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tap2jas/Tap2jas
C57BL/6JSfdAnu-Tap2jas/AnuApb 		absent CD8-positive, alpha-beta T cells J:104190
decreased CD8-positive, alpha-beta T cell number J:166104
Tap2m1Btlr/Tap2m1Btlr
C57BL/6J-Tap2m1Btlr 		abnormal cytotoxic T cell physiology J:159355
abnormal NK cell physiology J:159355
absent CD8-positive, alpha-beta T cells J:159355
decreased level of surface class I molecules J:159355
defective assembly of class I molecules J:159355
Tap2m2Btlr/Tap2m2Btlr
C57BL/6J-Tap2m2Btlr 		decreased CD8-positive, alpha-beta T cell number J:217145
increased CD4-positive, alpha-beta T cell number J:217145
Tap2m3Btlr/Tap2m3Btlr
C57BL/6J-Tap2m3Btlr 		decreased CD8-positive, alpha-beta T cell number J:254929
decreased CD8-positive, naive alpha-beta T cell number J:254929
decreased effector memory CD4-positive, alpha-beta T cell number J:254929
decreased NK T cell number J:254929
increased CD4-positive, alpha-beta T cell number J:254929
increased central memory CD8 positive, alpha-beta T cell number J:254929
Tap2M4Btlr/Tap2M4Btlr
C57BL/6J-Tap2M4Btlr 		increased CD4-positive, alpha-beta T cell number J:272847
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory