About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
MGI:98488
33 phenotypes from 4 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Slc6a6em1(IMPC)Mbp/Slc6a6em1(IMPC)Mbp
C57BL/6N-Slc6a6em1(IMPC)Mbp/MbpMmucd 		abnormal lymph node morphology J:211773
abnormal retina morphology J:211773
decreased erythrocyte cell number J:211773
decreased fasting circulating glucose level J:211773
decreased heart rate J:211773
decreased thigmotaxis J:211773
enlarged lymph nodes J:211773
impaired pupillary reflex J:211773
increased blood urea nitrogen level J:211773
increased circulating phosphate level J:211773
increased monocyte cell number J:211773
prolonged RR interval J:211773
Slc6a6m1Btlr/Slc6a6m1Btlr
C57BL/6J-Slc6a6m1Btlr 		decreased total retina thickness J:254927
Slc6a6tm1Dhau/Slc6a6tm1Dhau
involves: 129X1/SvJ * C57BL/6J 		abnormal vision J:74276
decreased circulating taurine level J:74276
decreased taurine level J:74276
increased susceptibility to age-related retinal degeneration J:74276
reduced female fertility J:74276
retina photoreceptor degeneration J:74276
Slc6a6tm1Jaz/Slc6a6tm1Jaz
involves: 129S2/SvPas * C57BL/6 		abnormal cardiovascular system physiology J:135159
abnormal muscle fiber morphology J:135159
abnormal myocardial fiber morphology J:135159
decreased body weight J:135159
decreased cardiac muscle contractility J:135159
decreased heart weight J:135159
decreased myocardial fiber size J:135159
decreased skeletal muscle fiber diameter J:135159
decreased skeletal muscle weight J:135159
dilated cardiomyopathy J:135159
dilated heart left ventricle J:135159
impaired exercise endurance J:135159
muscular atrophy J:135159
thin ventricular wall J:135159
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory