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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tbx1
T-box 1
MGI:98493
223 phenotypes from 21 alleles in 34 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * C57BL/6 * SJL 		abnormal cochlea morphology J:204435
abnormal common crus morphology J:204435
abnormal endolymphatic duct morphology J:204435
abnormal forebrain morphology J:204435
abnormal frontonasal prominence morphology J:204435
abnormal geniculate ganglion morphology J:204435
abnormal glossopharyngeal ganglion morphology J:204435
abnormal nasal placode morphology J:204435
abnormal optic vesicle formation J:204435
abnormal trigeminal ganglion morphology J:204435
abnormal vagus ganglion morphology J:204435
absent lateral semicircular canal J:204435
absent utricle J:204435
absent vestibular saccule J:204435
athymia J:204435
cochlear ganglion degeneration J:204435
perinatal lethality, complete penetrance J:204435
vestibular ganglion degeneration J:204435
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+
Tg(Pax2-cre)1Akg/0
involves: 129 * C57BL/6 * SJL 		abnormal cochlea morphology J:204435
abnormal common crus morphology J:204435
abnormal endolymphatic duct morphology J:204435
abnormal semicircular canal morphology J:204435
absent lateral semicircular canal J:204435
absent utricle J:204435
absent vestibular saccule J:204435
perinatal lethality, complete penetrance J:204435
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+
Tbx1tm6(cre)Bld/Tbx1+
involves: 129 * C57BL/6 * SJL 		normal cardiovascular system phenotype J:204435
normal hearing/vestibular/ear phenotype J:204435
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sortm1(Tbx1/GFP)Bem
Tbx1tm6(cre)Bld/Tbx1+
involves: 129 * C57BL/6 * SJL 		double outlet right ventricle J:204435
persistent truncus arteriosus J:204435
postnatal lethality, complete penetrance J:204435
ventricular septal defect J:204435
Hoxa3tm1(cre)Moon/Hoxa3+
Tbx1tm3Bld/Tbx1tm1Bld
involves: 129S7/SvEvBrd * C57BL/6 		persistent truncus arteriosus J:110620
Mesp1tm2(cre)Ysa/Mesp1+
Tbx1tm1Bld/Tbx1tm3Bld
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal accessory nerve morphology J:112457
abnormal aortic arch morphology J:112457
abnormal cardiac neural crest cell migration J:112457
abnormal cardiac outflow tract development J:112457
abnormal cranial neural crest cell migration J:112457
abnormal fourth pharyngeal pouch morphology J:112457
abnormal interventricular septum morphology J:112457
abnormal mandibular nerve branching J:112457
abnormal mesenchyme morphology J:112457
abnormal pharyngeal arch artery morphology J:112457
abnormal pharyngeal arch morphology J:112457
abnormal vagus nerve morphology J:112457
absent fourth pharyngeal arch J:112457
absent fourth pharyngeal arch artery J:112457
absent sixth pharyngeal arch J:112457
absent sixth pharyngeal arch artery J:112457
absent third pharyngeal arch J:112457
absent third pharyngeal arch artery J:112457
athymia J:112457
normal craniofacial phenotype J:112457
ear lobe hypoplasia J:112457
glossopharyngeal nerve hypoplasia J:112457
persistent truncus arteriosus J:112457
pharynx hypoplasia J:112457
second pharyngeal arch hypoplasia J:112457
thymus hypoplasia J:112457
Mesp1tm2(cre)Ysa/Mesp1+
Tbx1tm1Bld/Tbx1tm5Bld
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal neural crest cell migration J:112457
absent fourth pharyngeal arch J:112457
absent fourth pharyngeal arch artery J:112457
athymia J:112457
normal cardiovascular system phenotype J:112457
normal hearing/vestibular/ear phenotype J:112457
Nkx2-5tm1(cre)Rjs/Nkx2-5+
Tbx1tm1Bld/Tbx1tm3Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal pharyngeal arch artery morphology J:91013
absent fourth pharyngeal arch artery J:91013
normal craniofacial phenotype J:91013
decreased mitotic index J:91013
fourth pharyngeal arch artery hypoplasia J:91013
persistent truncus arteriosus J:91013
small thymus J:91013
Tbx1em1(IMPC)Mbp/Tbx1+
C57BL/6NCrl-Tbx1em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal eye morphology J:211773
abnormal pancreas morphology J:211773
abnormal placenta morphology J:211773
abnormal skin morphology J:211773
anophthalmia J:211773
microphthalmia J:211773
persistence of hyaloid vascular system J:211773
Tbx1em1(IMPC)Mbp/Tbx1em1(IMPC)Mbp
C57BL/6NCrl-Tbx1em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal placenta morphology J:211773
edema J:211773
embryonic growth retardation J:211773
preweaning lethality, complete penetrance J:211773
Tbx1m1Anu/?
involves: BALB/c * C57BL/6 * DBA/2 		bidirectional circling J:196547
head tilt J:196547
Tbx1m1H/Tbx1m1H
involves: C3H/HeH * C57BL/6J 		abnormal inner ear morphology J:169366
cleft palate J:169366
edema J:169366
persistent truncus arteriosus J:169366
small thymus J:169366
ventricular septal defect J:169366
Tbx1m1Jlk/Tbx1+
129/Sv-Tbx1m1Jlk 		no abnormal phenotype detected J:146769
Tbx1m1Jlk/Tbx1m1Jlk
129/Sv-Tbx1m1Jlk 		abnormal outer ear morphology J:146769
abnormal pharyngeal arch artery morphology J:146769
athymia J:146769
cleft palate J:146769
persistent truncus arteriosus J:146769
Tbx1m1Jlk/Tbx1tm1Bld
involves: 129 		abnormal outer ear morphology J:146769
abnormal pharyngeal arch artery morphology J:146769
athymia J:146769
cleft palate J:146769
persistent truncus arteriosus J:146769
Tbx1nmf219/Tbx1nmf219
C57BL/6J-Tbx1nmf219/J 		abnormal auditory brainstem response J:87349
abnormal cochlea morphology J:278988
abnormal common crus morphology J:278988
abnormal organ of Corti supporting cell differentiation J:278988
abnormal organ of Corti supporting cell morphology J:278988
abnormal posterior semicircular canal morphology J:278988
abnormal semicircular canal ampulla morphology J:278988
abnormal semicircular canal morphology J:278988
abnormal stria vascularis morphology J:278988
abnormal strial marginal cell morphology J:278988
absent strial marginal cells J:278988
circling J:87349
cochlear ganglion degeneration J:278988
collapsed Reissner membrane J:278988
deafness J:87349, J:278988
head bobbing J:87349
increased or absent threshold for auditory brainstem response J:278988
organ of Corti degeneration J:278988
small scala media J:278988
Tbx1tm1.1Dsr/Tbx1+
either: 129/Sv or (involves: 129/Sv * C57BL/6) 		abnormal aortic arch morphology J:93588
neonatal lethality, incomplete penetrance J:93588
Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
either: 129/Sv or (involves: 129/Sv * C57BL/6) 		aberrant origin of the right subclavian artery J:93588
abnormal hyoid bone morphology J:93588
abnormal inner ear morphology J:93588
abnormal middle ear ossicle morphology J:93588
abnormal stapes morphology J:93588
anotia J:93588
athymia J:93588
cleft secondary palate J:93588
decreased tympanic ring size J:93588
double aortic arch J:93588
double outlet right ventricle J:93588
fusion of basioccipital and basisphenoid bone J:93588
neonatal lethality, complete penetrance J:93588
palatal shelves fail to meet at midline J:93588
persistent truncus arteriosus J:93588
right aortic arch J:93588
small cricoid cartilage J:93588
ventricular septal defect J:93588
Tbx1tm1Bem/Tbx1+
B6.Cg-Tbx1tm1Bem 		abnormal motor capabilities/coordination/movement J:177772
abnormal response to novel object J:177772
abnormal social/conspecific interaction behavior J:177772
abnormal spatial working memory J:177772
decreased vocalization J:177772
increased thigmotaxis J:177772
Tbx1tm1Bem/Tbx1+
FVB.Cg-Tbx1tm1Bem 		abnormal cardiac outflow tract development J:91664
abnormal middle ear morphology J:91664
increased or absent threshold for auditory brainstem response J:91664
increased susceptibility to otitis media J:91664
Tbx1tm1Bem/Tbx1+
involves: 129 * C57BL/6 * CD-1 * SJL 		abnormal cardiovascular development J:172023
Tbx1tm1Bem/Tbx1+
involves: 129/Sv * C57BL/6J * FVB * SJL 		abnormal neuron differentiation J:89188
Tbx1tm1Bem/Tbx1+
involves: 129/Sv * C57BL/6J * SJL 		aberrant origin of the right subclavian artery J:67796
abnormal fourth pharyngeal arch morphology J:167713
cervical aortic arch J:67796
interrupted aortic arch J:67796
retroesophageal right subclavian artery J:67796
small pharyngeal arch J:167713
Tbx1tm1Bem/Tbx1tm1Bem
FVB.Cg-Tbx1tm1Bem 		abnormal inner ear morphology J:91664
abnormal middle ear morphology J:91664
absent masseter muscle J:91664
absent parathyroid glands J:91664
absent pterygoid muscle J:91664
absent ultimobranchial body J:91664
anotia J:91664
athymia J:91664
cleft palate J:91664
palatal shelves fail to meet at midline J:91664
persistent truncus arteriosus J:91664
right aortic arch J:91664
thymus hypoplasia J:91664
Tbx1tm1Bem/Tbx1tm1Bem
involves: 129 * C57BL/6 * CD-1 * SJL 		abnormal cardiovascular development J:172023
Tbx1tm1Bem/Tbx1tm1Bem
involves: 129/Sv * C57BL/6J * FVB * SJL 		abnormal cochlear ganglion morphology J:89188
abnormal inner ear morphology J:89188
abnormal neuron differentiation J:89188
otic vesicle hypoplasia J:89188
Tbx1tm1Bem/Tbx1tm1Bem
involves: 129/Sv * C57BL/6J * SJL 		abnormal pharyngeal pouch morphology J:167713
Tbx1tm1Bld/Tbx1+
B6.129S7-Tbx1tm1Bld 		abnormal lateral semicircular canal morphology J:154590
absent lateral semicircular canal J:154590
Tbx1tm1Bld/Tbx1+
B6.Cg-Tyrc-Brd Tbx1tm1Bld 		decreased prepulse inhibition J:110101
Tbx1tm1Bld/Tbx1+
involves: 129S7/SvEvBrd 		abnormal fourth pharyngeal arch artery morphology J:67409
Tbx1tm1Bld/Tbx1+
involves: 129S7/SvEvBrd * C57BL/6 		abnormal aortic arch morphology J:188772
abnormal fourth pharyngeal arch artery morphology J:67409
abnormal palate morphology J:188772
fourth pharyngeal arch artery hypoplasia J:110378
postnatal lethality J:110620
retroesophageal right subclavian artery J:188772
Tbx1tm1Bld/Tbx1+
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		abnormal cardiac outflow tract development J:314464
abnormal right subclavian artery morphology J:314464
normal mortality/aging J:314464
perimembraneous ventricular septal defect J:314464
Tbx1tm1Bld/Tbx1+
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal artery development J:212881
abnormal blood vessel morphology J:212881
abnormal fourth pharyngeal arch artery morphology J:212881
abnormal pharyngeal arch artery morphology J:212881
increased vascular smooth muscle cell proliferation J:212881
vascular smooth muscle hypoplasia J:212881
Tbx1tm1Bld/Tbx1tm1Bld
involves: 129S7/SvEvBrd 		abnormal ear morphology J:204435
abnormal endolymphatic duct morphology J:204435
abnormal fourth pharyngeal arch morphology J:110378
abnormal inner ear morphology J:146769
abnormal lymphangiogenesis J:159824
abnormal lymphatic vessel morphology J:159824
abnormal outer ear morphology J:146769
abnormal palatal shelf fusion at midline J:110378
absent fourth pharyngeal arch artery J:67409
absent sixth pharyngeal arch artery J:67409
absent third pharyngeal arch artery J:67409
athymia J:146769
cleft palate J:146769
increased apoptosis J:159824
lymphangiectasis J:159824
persistent truncus arteriosus J:146769
skin edema J:159824
small second pharyngeal arch J:67409
Tbx1tm1Bld/Tbx1tm1Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal accessory nerve morphology J:76173
abnormal conotruncus morphology J:76173
abnormal conotruncus septation J:76173
abnormal cranial nerve morphology J:76173
abnormal dorsal aorta morphology J:67409
abnormal fetal atrioventricular canal morphology J:76173
abnormal fourth pharyngeal arch artery morphology J:110378
abnormal glossopharyngeal ganglion morphology J:76173
abnormal glossopharyngeal nerve morphology J:76173
abnormal mandibular nerve branching J:76173
abnormal middle ear morphology J:85072
abnormal neural crest cell migration J:76173
abnormal outer ear morphology J:85072
abnormal palatal mesenchymal cell proliferation J:317609
abnormal palatal shelf size J:317609
abnormal palate development J:317609
abnormal pharyngeal arch artery morphology J:67409
abnormal pharyngeal arch morphology J:67409
abnormal pharyngeal pouch morphology J:76173
abnormal secondary palate development J:317609
abnormal trigeminal nerve morphology J:76173
abnormal truncus arteriosus septation J:76173
abnormal vagus ganglion morphology J:76173
abnormal vagus nerve morphology J:76173
abnormal vestibulocochlear ganglion morphology J:85072
absent cochlea J:85072
absent fourth pharyngeal arch artery J:67409
absent inner ear J:85072
absent inner ear vestibule J:85072
absent pharyngeal arches J:76173
absent semicircular canals J:85072
absent sixth pharyngeal arch artery J:67409
absent third pharyngeal arch artery J:67409
cleft secondary palate J:91013, J:110378
decreased palatal shelf size J:317609
fusion of glossopharyngeal and vagus nerve J:76173
glossopharyngeal nerve hypoplasia J:76173
increased palatal shelf size J:317609
perimembraneous ventricular septal defect J:76173
persistent truncus arteriosus J:76173
pharynx hypoplasia J:76173
retroesophageal right subclavian artery J:76173
small otic vesicle J:85072
small second pharyngeal arch J:67409
Tbx1tm1Bld/Tbx1tm2.1Bem
Tfap2atm1(cre)Moon/Tfap2a+
either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL) 		aberrant origin of the right subclavian artery J:154590
abnormal aortic arch morphology J:154590
abnormal cardiac outflow tract development J:154590
athymia J:154590
cleft palate J:154590
persistent truncus arteriosus J:154590
thymus hypoplasia J:154590
ventricular septal defect J:154590
Tbx1tm1Bld/Tbx1tm2Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal heart development J:91013
normal craniofacial phenotype J:91013
Tbx1tm1Bld/Tbx1tm3Bld
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal lymphangiogenesis J:159824
abnormal lymphatic vessel morphology J:159824
Tbx1tm1Bld/Tbx1tm3Bld
Tg(Myh6-cre)2182Mds/0
involves: 129S7/SvEvBrd * C57BL/6 		abnormal aortic arch morphology J:91013
Tbx1tm1Bld/Tbx1tm3Bld
Tg(Tek-cre)1Ywa/0
involves: 129S7/SvEvBrd * C57BL/6 		abnormal aortic arch morphology J:91013
Tbx1tm1Bld/Tbx1tm3Bld
Tg(Tek-cre)1Ywa/0
involves: 129S7/SvEvBrd * C57BL/6 * SJL 		abnormal lymphangiogenesis J:159824
abnormal lymphatic vessel morphology J:159824
chylous ascites J:159824
dehydration J:159824
postnatal growth retardation J:159824
postnatal lethality, complete penetrance J:159824
Tbx1tm1Bld/Tbx1tm5Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal aortic arch morphology J:112457
abnormal cardiovascular system morphology J:112457
abnormal fourth pharyngeal arch morphology J:112457
abnormal pharyngeal arch artery morphology J:112457
abnormal sixth pharyngeal arch morphology J:112457
abnormal third pharyngeal arch morphology J:112457
absent fourth pharyngeal arch artery J:112457
absent sixth pharyngeal arch artery J:112457
absent third pharyngeal arch artery J:112457
athymia J:112457
ear lobe hypoplasia J:112457
persistent truncus arteriosus J:112457
pharynx hypoplasia J:112457
small second pharyngeal arch J:112457
ventricular septal defect J:112457
Tbx1tm1Bld/Tbx1tm6(cre)Bld
involves: 129S7/SvEvBrd 		persistent truncus arteriosus J:204435
ventricular septal defect J:204435
Tbx1tm1Bld/Tbx1tm7.1Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal craniofacial development J:166754
Tbx1tm1Bld/Tbx1tm8.1Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal craniofacial development J:166754
Tbx1tm1Dsr/Tbx1+
either: 129/Sv or (involves: 129/Sv * C57BL/6) 		aberrant origin of the right subclavian artery J:93588
interrupted aortic arch J:93588
neonatal lethality, incomplete penetrance J:93588
Tbx1tm1Dsr/Tbx1tm1Dsr
either: 129/Sv or (involves: 129/Sv * C57BL/6) 		aberrant origin of the right subclavian artery J:93588
abnormal inner ear morphology J:93588
abnormal middle ear ossicle morphology J:93588
abnormal stapes morphology J:93588
athymia J:93588
decreased tympanic ring size J:93588
double aortic arch J:93588
double outlet right ventricle J:93588
fusion of basioccipital and basisphenoid bone J:93588
neonatal lethality, complete penetrance J:93588
persistent truncus arteriosus J:93588
right aortic arch J:93588
small ears J:93588
ventricular septal defect J:93588
Tbx1tm1Pa/Tbx1+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ 		abnormal fourth pharyngeal arch artery morphology J:70730
Tbx1tm1Pa/Tbx1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster 		abnormal fourth pharyngeal arch artery morphology J:70730
Tbx1tm1Pa/Tbx1tm1Pa
either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster) 		abnormal cervical atlas morphology J:70730
abnormal cranium morphology J:70730
abnormal ear shape J:70730
abnormal facial morphology J:70730
abnormal fourth pharyngeal arch morphology J:70730
abnormal middle ear ossicle morphology J:70730
abnormal palatal shelf fusion at midline J:70730
abnormal pharyngeal arch artery morphology J:70730
abnormal pharyngeal arch morphology J:70730
abnormal pharyngeal pouch morphology J:70730
abnormal semicircular canal morphology J:70730
abnormal temporal bone morphology J:70730
abnormal third pharyngeal arch morphology J:70730
abnormal thymus development J:70730
abnormal tympanic ring morphology J:70730
abnormal upper incisor morphology J:70730
abnormal zygomatic arch morphology J:70730
absent arcus anterior J:70730
absent mandibular coronoid process J:70730
absent outer ear J:70730
absent parathyroid glands J:70730
absent second pharyngeal arch J:70730
absent upper incisors J:70730
athymia J:70730
cleft secondary palate J:70730
decreased embryo size J:70730
double aortic arch J:70730
fusion of basioccipital and basisphenoid bone J:70730
hydrops fetalis J:70730
lowered ear position J:70730
micrognathia J:70730
neonatal lethality, complete penetrance J:70730
persistent truncus arteriosus J:70730
pharynx stenosis J:70730
respiratory failure J:70730
right aortic arch J:70730
short mandible J:70730
short neck J:70730
small cricoid cartilage J:70730
small otic vesicle J:70730
small thyroid cartilage J:70730
Tbx1tm1Pa/Tbx1tm1Pa
involves: 129 * C57BL/6 		abnormal external auditory canal morphology J:96463
abnormal facial nerve morphology J:96463
abnormal hyoid bone morphology J:96463
abnormal incus morphology J:96463
abnormal malleus morphology J:96463
abnormal middle ear morphology J:96463
abnormal neural crest cell migration J:96463
abnormal otic capsule morphology J:96463
abnormal pharyngeal arch morphology J:96463
abnormal thyroid cartilage morphology J:96463
abnormal trigeminal nerve morphology J:96463
abnormal vestibulocochlear nerve morphology J:96463
absent cochlea J:96463
absent inner ear vestibule J:96463
absent second pharyngeal arch J:96463
absent stapes J:96463
absent third pharyngeal arch J:96463
decreased tympanic ring size J:96463
dilated endolymphatic duct J:96463
inner ear hypoplasia J:96463
malleus hypoplasia J:96463
small otic vesicle J:96463
thin malleus neck J:96463
Tbx1tm1Pa/Tbx1tm1Pa
involves: 129S1/Sv * 129X1/SvJ 		abnormal hypoglossal cord morphology J:94411
abnormal laryngeal muscle morphology J:94411
abnormal myogenesis J:94411
abnormal pharyngeal muscle morphology J:150130
Tbx1tm2.1Bem/Tbx1+
Tfap2atm1(cre)Moon/Tfap2a+
either: (involves: 129/Sv * C57BL/6 * C57BL/6J * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL) 		fourth pharyngeal arch artery hypoplasia J:154590
Tbx1tm2.1Bem/Tbx1tm2.1Bem
H2az2Tg(Wnt1-cre)11Rth/H2az2+
either: (involves: 129/Sv * C57BL/6 * C57BL/6J * CBA/J * SJL) or (involves: 129/Sv * C57BL/6J * CBA/J * CD-1 * SJL) 		no abnormal phenotype detected J:154590
Tbx1tm2.1Bem/Tbx1tm2.2Bem
Foxg1tm1(cre)Skm/Foxg1+
involves: 129 * C57BL/6J * SJL * Swiss Webster 		abnormal aortic arch morphology J:105980
abnormal cardiac outflow tract development J:105980
abnormal craniofacial bone morphology J:109536
abnormal endolymphatic duct morphology J:109536
abnormal middle ear development J:109536
abnormal pharyngeal pouch morphology J:109536
abnormal vestibulocochlear ganglion morphology J:109536
absent cochlea J:109536
absent inner ear J:109536
absent inner ear vestibule J:109536
absent masseter muscle J:105980
absent middle ear ossicles J:105980, J:109536
absent outer ear J:105980, J:109536
absent parathyroid glands J:105980
absent pterygoid muscle J:105980
absent semicircular canals J:109536
absent tubotympanic recess J:109536
absent tympanic ring J:105980, J:109536
absent zygomatic arch J:105980
athymia J:105980
cleft secondary palate J:105980, J:109536
fusion of basioccipital and basisphenoid bone J:105980, J:109536
hyoid bone hypoplasia J:105980
inner ear hypoplasia J:109536
neonatal lethality, complete penetrance J:105980, J:109536
otic capsule hypoplasia J:109536
otic vesicle hypoplasia J:109536
persistent truncus arteriosus J:105980
pharynx hypoplasia J:105980
retroesophageal right subclavian artery J:105980
short mandible J:105980
skin edema J:105980
small otic vesicle J:109536
small thyroid gland J:105980
temporal bone hypoplasia J:105980
ventricular septal defect J:105980
Tbx1tm2.1Bem/Tbx1tm2.2Bem
Tg(Pax2-cre)1Akg/0
involves: 129 * C57BL/6 * SJL 		abnormal inner ear morphology J:109536
abnormal vestibulocochlear ganglion morphology J:109536
absent cochlea J:109536
absent inner ear J:109536
absent inner ear vestibule J:109536
absent semicircular canals J:109536
normal craniofacial phenotype J:109536
normal embryo phenotype J:109536
increased or absent threshold for auditory brainstem response J:109536
inner ear hypoplasia J:109536
otic vesicle hypoplasia J:109536
sensorineural hearing loss J:109536
small otic vesicle J:109536
Tbx1tm2.2Bem/Tbx1tm2.2Bem
involves: 129/Sv * C57BL/6J * SJL * Swiss Webster 		abnormal interventricular septum morphology J:105980
absent facial muscle J:105980
neonatal lethality, complete penetrance J:105980
Tbx1tm2Bem/Tbx1tm2Bem
involves: 129/Sv * C57BL/6J * SJL 		abnormal craniofacial bone morphology J:105980
Tbx1tm2Bld/Tbx1+
involves: 129S7/SvEvBrd * C57BL/6 		abnormal aortic arch morphology J:91013
Tbx1tm2Bld/Tbx1tm2Bld
involves: 129S7/SvEvBrd * C57BL/6 		abnormal heart development J:91013
abnormal pharyngeal arch morphology J:91013
ventricular septal defect J:91013
Tbx1tm3Bld/Tbx1tm3Bld
involves: 129S7/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:91013
Tbx1tm4(cre/Esr1*)Bld/Tbx1+
involves: 129P2/OlaHsd * 129S7/SvEvBrd 		abnormal aortic arch morphology J:110620
Tbx1tm6(cre)Bld/Tbx1+
involves: C57BL/6J 		abnormal blood vessel morphology J:212881
Tbx1tm7.1Bld/Tbx1tm7.1Bld
involves: 129S7/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:166754
Tbx1tm8.1Bld/Tbx1tm8.1Bld
involves: 129S7/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:166754
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory