Tbxa2r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbxa2r
thromboxane A2 receptor
MGI:98496

20 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbxa2r^tm1Cof/Tbxa2r^tm1.1Bhk Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * SJL	abnormal airway resistance	J:183333
Tbxa2r^tm1Cof/Tbxa2r^tm1.1Bhk Tg(Tagln-cre)1Her/0 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * SJL	abnormal airway resistance	J:183333
Tbxa2r^tm1Cof/Tbxa2r^tm1Cof C.129P2(B6)-Tbxa2r^tm1Cof	abnormal blood vessel physiology	J:79049
	abnormal platelet physiology	J:79049
	abnormal thromboxane level	J:79049
Tbxa2r^tm1Cof/Tbxa2r^tm1Cof either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * 129S/SvEv)	abnormal cardiovascular system physiology	J:52125
	abnormal platelet aggregation	J:52125
	normal immune system phenotype	J:52125
	increased bleeding time	J:52125
	normal mortality/aging	J:52125
	normal reproductive system phenotype	J:52125
Tbxa2r^tm1Cof/Tbxa2r^tm1Cof involves: 129P2/OlaHsd	abnormal airway resistance	J:183333
Tbxa2r^tm1Sna/Tbxa2r^tm1Sna B6.Cg-Tbxa2r^tm1Sna	edema	J:197334
Tbxa2r^tm1Sna/Tbxa2r^tm1Sna B6.Cg-Tbxa2r^tm1Sna	increased susceptibility to type I hypersensitivity reaction	J:197334
Tbxa2r^tm1Sna/Tbxa2r^tm1Sna either: (involves: 129/Ola * BALB/c) or (involves: 129/Ola * C57BL/6)	abnormal cervical lymph node morphology	J:84085
	abnormal immune serum protein physiology	J:84085
	abnormal immune system organ morphology	J:84085
	abnormal immune system physiology	J:84085
	abnormal lymph node morphology	J:84085
	abnormal type I hypersensitivity reaction	J:84085
	enlarged lymph nodes	J:84085
	enlarged spleen	J:84085

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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