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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tcra-J
T cell receptor alpha, joining region
MGI:98555
44 phenotypes from 7 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tcra-Jtm1Jpdv/Tcra-Jtm1Jpdv
involves: 129P2/OlaHsd 		abnormal T cell differentiation J:77518
Tcra-Jtm1Slek/Tcra-Jtm1Slek
involves: 129P2/OlaHsd 		abnormal T cell differentiation J:101398
decreased double-positive T cell number J:101398
decreased single-positive T cell number J:101398
increased double-negative T cell number J:101398
increased thymocyte number J:101398
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
B6.129-Tcra-Jtm1Tgi 		abnormal cornea morphology J:132503
abnormal female reproductive system physiology J:59892
abnormal hepatocyte morphology J:135830
cornea opacity J:132503
decreased activated T cell number J:99107
decreased airway responsiveness J:121037
decreased B cell number J:99107
decreased circulating alanine transaminase level J:135830
decreased circulating interleukin-5 level J:121037
decreased hepatocyte apoptosis J:135830
decreased IgE level J:121037
decreased IgG level J:99107
decreased susceptibility to induced arthritis J:99107
decreased susceptibility to induced choroidal neovascularization J:138197
focal hepatic necrosis J:135830
increased incidence of corneal inflammation J:132503
liver inflammation J:135830
lung inflammation J:121037
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
C.129-Tcra-Jtm1Tgi 		abnormal interleukin secretion J:184570
decreased airway responsiveness J:184570
decreased interleukin-5 secretion J:184570
decreased interleukin-9 secretion J:184570
decreased interleukin-10 secretion J:184570
decreased interleukin-13 secretion J:184570
decreased interleukin-17 secretion J:184570
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
involves: 129S1/Sv * 129X1/SvJ 		normal cardiovascular system phenotype J:134875
decreased circulating interferon-gamma level J:155199
decreased interferon-gamma secretion J:155199
decreased susceptibility to bacterial infection J:155199
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
involves: 129S1/Sv * 129X1/SvJ * BALB/c 		abnormal airway responsiveness J:84720
abnormal eosinophil cell number J:84720
abnormal immune serum protein physiology J:84720
abnormal interleukin secretion J:84720
decreased IgE level J:84720
decreased interleukin-4 secretion J:84720
decreased interleukin-13 secretion J:84720
impaired liver regeneration J:105977
liver inflammation J:105977
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal liver morphology J:93915
decreased NK T cell number J:89695
decreased physiological sensitivity to xenobiotic J:93915
increased susceptibility to xenobiotic induced morbidity/mortality J:89695
lung inflammation J:89695
pulmonary fibrosis J:89695
Tcra-Jtm2.3Krg/Tcra-Jtm2.3Krg
involves: 129S/SvEv * C57BL/6 		abnormal T cell receptor alpha chain V-J recombination J:147326
Tcra-Jtm3.1Krg/Tcra-Jtm3.1Krg
involves: 129S6/SvEvTac 		abnormal T cell differentiation J:128344
Tcra-Jtm4.1Krg/Tcra-Jtm4.1Krg
involves: 129S6/SvEvTac 		abnormal T cell receptor alpha chain V-J recombination J:147326
Tcra-Jtm5Krg/Tcra-Jtm5Krg
involves: 129S6/SvEvTac 		abnormal T cell receptor alpha chain V-J recombination J:147326
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory