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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cripto
cripto, EGF-CFC family member
MGI:98658
51 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Criptotm1Eda/Criptotm1Eda
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6) 		abnormal gastrulation J:186907
abnormal mesoderm development J:186907
abnormal primitive streak formation J:186907
embryonic growth arrest J:186907
Criptotm1Eda/Criptotm1Eda
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal amnion morphology J:51595
abnormal cell adhesion J:51595
abnormal chorion morphology J:51595
abnormal developmental patterning J:51595
abnormal embryonic neuroepithelium morphology J:51595
abnormal embryonic tissue morphology J:51595
abnormal extraembryonic tissue morphology J:51595
abnormal heart development J:51595
abnormal mesoderm development J:51595
abnormal rostral-caudal axis patterning J:51595
abnormal visceral yolk sac blood island morphology J:51595
absent somites J:51595
absent vitelline blood vessels J:51595
decreased fibroblast proliferation J:51595
normal embryo phenotype J:51595
embryonic lethality, complete penetrance J:51595
short rostral-caudal axis J:51595
Criptotm1Mms/Criptotm1Mms
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss) 		abnormal embryonic neuroepithelium morphology J:50343
abnormal gastrulation J:50343
abnormal germ layer development J:50343
abnormal heart development J:50343
abnormal mesoderm development J:50343
abnormal rostral-caudal axis patterning J:50343
abnormal visceral endoderm morphology J:50343
absent mesoderm J:50343
absent somites J:50343
embryonic lethality during organogenesis, complete penetrance J:50343
failure of primitive streak formation J:50343
Criptotm1Mms/Criptotm2Mms
involves: 129S6/SvEvTac * C57BL/6 		abnormal endoderm development J:104418
abnormal mesendoderm development J:104418
absent anterior definitive endoderm J:104418
absent notochord J:104418
absent prechordal plate J:104418
cyclopia J:104418
decreased forebrain size J:104418
decreased midbrain size J:104418
fused somites J:104418
holoprosencephaly J:104418
premature death J:104418
rostral body truncation J:104418
Criptotm2.2Mms/Criptotm2.2Mms
involves: 129S6/SvEvTac * FVB/N 		no abnormal phenotype detected J:104418
Criptotm2Mms/Criptotm2.1Mms
involves: 129S6/SvEvTac * C57BL/6 		abnormal endoderm development J:104418
abnormal mesendoderm development J:104418
absent anterior definitive endoderm J:104418
absent notochord J:104418
absent prechordal plate J:104418
cyclopia J:104418
decreased forebrain size J:104418
decreased midbrain size J:104418
fused somites J:104418
holoprosencephaly J:104418
premature death J:104418
rostral body truncation J:104418
Pgrtm2(cre)Lyd/Pgr+
Criptotm2.2Mms/Criptotm2.2Mms
involves: 129/Sv * C57BL/6N * CD-1 		abnormal decidualization J:324146
abnormal embryo attachment J:324146
abnormal endometrial gland morphology J:324146
abnormal luminal closure J:324146
abnormal pregnancy J:324146
abnormal uterine environment J:324146
abnormal uterine-embryonic axis J:324146
decreased litter size J:324146
delayed embryo implantation J:324146
endometrium inflammation J:324146
failure of embryo implantation J:324146
female infertility J:324146
reduced female fertility J:324146
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory