Tek Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tek
TEK receptor tyrosine kinase
MGI:98664

30 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Rasa1^tm1Paw/Rasa1^tm1Paw Tek^tm1Dmt/Tek^tm1Dmt either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal dorsal aorta morphology	J:29825
	abnormal visceral yolk sac morphology	J:29825
	abnormal vitelline vascular remodeling	J:29825
	absent vitelline blood vessels	J:29825
	distended pericardium	J:29825
	hemorrhage	J:29825
Tek^tm1.1Vlcg/Tek^tm1.1Vlcg Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/? Tg(tetO-cre)1Jaw/0 involves: 129 * C57BL/6NCr	abnormal anterior eye segment morphology	J:217296
	buphthalmos	J:217296
	increased cornea size	J:217296
	increased eye anterior chamber depth	J:217296
Tek^tm1Ber/Tek^tm1Ber involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal definitive hematopoiesis	J:99096
	abnormal heart development	J:99096
	abnormal vitelline vasculature morphology	J:99096
	absent myocardial trabeculae	J:99096
	embryonic lethality during organogenesis, complete penetrance	J:99096
	failure of vascular branching	J:99096
Tek^tm1Dmt/Tek⁺ Tie1^tm1Jpa/Tie1^tm1Jpa involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal cardiovascular development	J:54983
	abnormal heart development	J:54983
	abnormal vascular development	J:54983
	congestive heart failure	J:54983
	edema	J:54983
	embryonic lethality during organogenesis, complete penetrance	J:54983
	enlarged pericardium	J:54983
	heart hemorrhage	J:54983
	hemorrhage	J:54983
Tek^tm1Dmt/Tek^tm1Dmt Tie1^tm1Jpa/Tie1^tm1Jpa involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal blood vessel morphology	J:54983
	abnormal forebrain development	J:54983
	abnormal heart development	J:54983
	abnormal myocardial trabeculae morphology	J:54983
	abnormal somite development	J:54983
	abnormal vascular development	J:54983
	abnormal vitelline vascular remodeling	J:54983
	abnormal vitelline vasculature morphology	J:54983
	absent organized vascular network	J:54983
	congestive heart failure	J:54983
	decreased angiogenesis	J:54983
	decreased embryo size	J:54983
	edema	J:54983
	embryo tissue necrosis	J:54983
	embryonic lethality during organogenesis, complete penetrance	J:54983
	enlarged pericardium	J:54983

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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