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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tgfb2
transforming growth factor, beta 2
MGI:98726
124 phenotypes from 1 allele in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tgfb2tm1Doe/Tgfb2+
involves: 129/Sv * 129P2/OlaHsd * Black Swiss * C57BL/6J 		decreased dopamine level J:108007
decreased dopaminergic neuron number J:108007
Tgfb2tm1Doe/Tgfb2+
involves: 129P2/OlaHsd 		abnormal small intestinal villus morphology J:76342
decreased enterocyte apoptosis J:76342
Tgfb2tm1Doe/Tgfb2+
involves: 129P2/OlaHsd * Black Swiss 		abnormal bulbourethral gland morphology J:78547
abnormal bulbourethral gland physiology J:78547
abnormal spermatogenesis J:78547
bulbourethral gland cyst J:78547
bulbourethral gland hyperplasia J:78547
oligozoospermia J:78547
prostate gland anterior lobe hyperplasia J:78547
teratozoospermia J:78547
Tgfb2tm1Doe/Tgfb2+
STOCK Tgfb2tm1Doe/J 		abnormal aorta wall morphology J:188799
aortic aneurysm J:188799
dilated aorta bulb J:188799
Tgfb2tm1Doe/Tgfb2tm1Doe
involves: 129P2/OlaHsd 		normal limbs/digits/tail phenotype J:76541
Tgfb2tm1Doe/Tgfb2tm1Doe
involves: 129P2/OlaHsd * Black Swiss 		aberrant origin of the right subclavian artery J:103391
abnormal aorta morphology J:103391
abnormal atrioventricular cushion morphology J:103391
abnormal atrioventricular valve morphology J:41682, J:103391
abnormal cardiac outflow tract development J:103391
abnormal cardiovascular development J:103391
abnormal clavicle morphology J:41682
abnormal cochlea morphology J:41682
abnormal cochlear ganglion morphology J:41682
abnormal cornea posterior stroma morphology J:73681
abnormal cornea stroma morphology J:73681
abnormal craniofacial bone morphology J:41682
abnormal eye posterior chamber morphology J:41682
abnormal femur morphology J:41682
abnormal heart septum morphology J:103391
abnormal heart ventricle outflow tract morphology J:103391
abnormal humerus morphology J:41682
abnormal iris stroma morphology J:73681
abnormal kidney morphology J:41682
abnormal limb morphology J:41682
abnormal macrophage physiology J:73681
abnormal mandible morphology J:41682
abnormal myocardium layer morphology J:41682, J:103391
abnormal neurocranium morphology J:41682
abnormal renal tubule epithelium morphology J:41682
abnormal retina neuronal layer morphology J:73681
abnormal rib morphology J:41682
abnormal scala vestibuli morphology J:41682
abnormal semilunar valve morphology J:41682, J:103391
abnormal sternum morphology J:41682
abnormal thoracic cage shape J:41682
abnormal trochanter morphology J:41682
abnormal truncus arteriosus septation J:103391
abnormal uterine horn morphology J:41682
abnormal xiphoid process morphology J:41682
absent alisphenoid bone J:41682
absent cornea endothelium J:73681
absent deltoid tuberosity J:41682
absent Descemet membrane J:73681
absent eye anterior chamber J:73681
absent interdental cells J:41682
absent kidney J:41682
absent mandibular angle J:41682
absent maxillary shelf J:41682
absent occipital bone J:41682
absent pterygoid process J:41682
absent Rosenthal canal J:41682
absent spiral limbus J:41682
aortic arch hypoplasia J:103391
ascending aorta hypoplasia J:41682, J:103391
atelectasis J:41682
atrioventricular septal defect J:103391
cleft secondary palate J:41682
complete atrioventricular septal defect J:103391
cyanosis J:41682
decreased body weight J:41682
decreased cornea stroma thickness J:41682, J:73681
decreased cornea thickness J:73681
dilated heart right ventricle J:41682, J:103391
dilated renal tubule J:41682
dilated respiratory conducting tube J:41682
double inlet heart left ventricle J:41682
double outlet right ventricle J:41682, J:103391
ectopic adrenal gland J:41682
ectopic testis J:41682
failure of atrioventricular cushion closure J:103391
failure of heart looping J:103391
failure of palatal shelf elevation J:41682
fused cornea and lens J:73681
heart valve hyperplasia J:103391
hydronephrosis J:41682
increased urine protein level J:41682
inlet ventricular septal defect J:41682, J:103391
interrupted aortic arch J:103391
interrupted aortic arch, type b J:103391
large fontanelles J:41682
neonatal lethality, complete penetrance J:41682, J:73681
ostium primum atrial septal defect J:103391
patent aortic valve J:41682
patent pulmonary valve J:41682
perimembraneous ventricular septal defect J:103391
perinatal lethality, incomplete penetrance J:41682
persistence of hyaloid vascular system J:73681
persistent right dorsal aorta J:103391
pulmonary artery hypoplasia J:103391
respiratory distress J:41682
retina hyperplasia J:41682
retrognathia J:41682
rib fusion J:41682
short mandible J:41682
short radius J:41682
short ulna J:41682
small frontal bone J:41682
small interparietal bone J:41682
small mandibular condyloid process J:41682
small mandibular coronoid process J:41682
small olecranon J:41682
small parietal bone J:41682
small temporal bone J:41682
spina bifida occulta J:41682
testis hypoplasia J:41682
thick aortic valve cusps J:103391
thick mitral valve J:103391
thick pulmonary valve cusps J:103391
thick tricuspid valve J:103391
trabecula carnea hypoplasia J:41682
vitreous body deposition J:73681
Tgfb2tm1Doe/Tgfb2tm1Doe
involves: 129P2/OlaHsd * C57BL/6 		primary vitreous hyperplasia J:149526
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory