Tgfb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tgfb2
transforming growth factor, beta 2
MGI:98726

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn2a^tm1(GFP)Cjs/Cdkn2a^tm1(GFP)Cjs Tgfb2^tm1Doe/Tgfb2⁺ involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	primary vitreous hyperplasia	J:149526
Cdkn2a^tm1(GFP)Cjs/Cdkn2a^tm1(GFP)Cjs Tgfb2^tm1Doe/Tgfb2^tm1Doe involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	primary vitreous hyperplasia	J:149526
Cdkn2a^tm1Cjs/Cdkn2a⁺ Tgfb2^tm1Doe/Tgfb2^tm1Doe involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	primary vitreous hyperplasia	J:149526
Cdkn2a^tm1Sxs/Cdkn2a⁺ Tgfb2^tm1Doe/Tgfb2^tm1Doe involves: 129/Sv * 129P2/OlaHsd * C57BL/6	primary vitreous hyperplasia	J:149526
Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tgfb2^tm1Doe/Tgfb2⁺ B6.Cg-Tgfb2^tm1Doe H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama	abnormal aqueous drainage system morphology	J:152572
	abnormal canal of Schlemm morphology	J:152572
	abnormal trabecular meshwork morphology	J:152572
	normal mortality/aging	J:152572
	ocular hypertension	J:152572
Fbn1^tm1Hcd/Fbn1⁺ Tgfb2^tm1Doe/Tgfb2⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal aorta wall morphology	J:188799
	aortic aneurysm	J:188799
	dilated aorta bulb	J:188799
	normal growth/size/body region phenotype	J:188799
Tgfb2^tm1Doe/Tgfb2⁺ Tgfb3^tm1Doe/Tgfb3⁺ involves: 129P2/OlaHsd	abnormal small intestinal villus morphology	J:76342
	decreased enterocyte apoptosis	J:76342
Tgfb2^tm1Doe/Tgfb2⁺ Tgfb3^tm1Doe/Tgfb3^tm1Doe involves: 129P2/OlaHsd	normal limbs/digits/tail phenotype	J:76541
	normal vision/eye phenotype	J:105113
Tgfb2^tm1Doe/Tgfb2^tm1Doe Tgfb3^tm1Doe/Tgfb3⁺ involves: 129P2/OlaHsd	abnormal cartilage development	J:76541
	abnormal cornea morphology	J:105113
	abnormal eye posterior chamber morphology	J:105113
	abnormal interdigital cell death	J:76541
	abnormal lens epithelium morphology	J:105113
	abnormal retina inner nuclear layer morphology	J:105113
	abnormal retina neuronal layer morphology	J:105113
	decreased cornea stroma thickness	J:105113
	decreased retina apoptosis	J:105113
	interdigital webbing	J:76541
Tgfb2^tm1Doe/Tgfb2^tm1Doe Tgfb3^tm1Doe/Tgfb3^tm1Doe involves: 129P2/OlaHsd	abnormal cartilage development	J:76541
	abnormal chondrocyte morphology	J:76541
	abnormal cornea morphology	J:105113
	abnormal digit development	J:76541
	abnormal eye posterior chamber morphology	J:105113
	abnormal interdigital cell death	J:76541
	abnormal lens epithelium morphology	J:105113
	abnormal retina apoptosis	J:105113
	abnormal retina inner nuclear layer morphology	J:105113
	abnormal retina neuronal layer morphology	J:105113
	decreased cornea stroma thickness	J:105113
	decreased cornea thickness	J:105113
	interdigital webbing	J:76541

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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