Tgm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tgm2
transglutaminase 2, C polypeptide
MGI:98731

30 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr 129(B6)-Tgm2^tm1.1Rmgr	normal growth/size/body region phenotype	J:200838
Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr 129(B6)-Tgm2^tm1.1Rmgr	normal homeostasis/metabolism phenotype	J:200838
Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr B6.129S1-Tgm2^tm1.1Rmgr	normal homeostasis/metabolism phenotype	J:200838
Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr B6.129S1-Tgm2^tm1.1Rmgr	increased body weight	J:200838
Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr involves: 129S1/SvImJ * C57BL/6	abnormal cell adhesion	J:95130
	abnormal T cell physiology	J:95130
Tgm2^tm1Gml/Tgm2^tm1Gml involves: 129X1/SvJ * C57BL/6	decreased circulating insulin level	J:78633
	decreased erythrocyte cell number	J:75566
	decreased hematocrit	J:75566
	hyperglycemia	J:78633
	impaired glucose tolerance	J:78633
	increased insulin sensitivity	J:78633
	increased physiological sensitivity to xenobiotic	J:82489
	increased susceptibility to induced morbidity/mortality	J:82489
Tgm2^tm1Gml/Tgm2^tm1Gml involves: C57BL/6	abnormal cardiovascular system physiology	J:126414
	abnormal mitochondrial ATP synthesis coupled electron transport	J:126414, J:131975
	abnormal response to cardiac infarction	J:126414
	normal cardiovascular system phenotype	J:131975
	decreased susceptibility to endotoxin shock	J:131975
	decreased susceptibility to induced morbidity/mortality	J:131975
	disorganized myocardium	J:131975
	normal immune system phenotype	J:131975
	increased macrophage cell number	J:131975
	increased myocardial infarct size	J:126414
	increased tumor growth/size	J:126131
	premature death	J:126131
	normal renal/urinary system phenotype	J:131975
	ventricular fibrillation	J:126414
Tgm2^tm1Gml/Tgm2^tm1Gml involves: C57BL/6 * DBA/1LacJ	abnormal thymus morphology	J:132254
	normal homeostasis/metabolism phenotype	J:132254
	impaired macrophage phagocytosis	J:132254
Tgm2^tm1Syki/Tgm2^tm1Syki involves: 129P2/OlaHsd * C57BL/6	decreased susceptibility to injury	J:167049
Tgm2^tm2.1Rmgr/Tgm2^tm2.1Rmgr involves: C57BL/6 * C57BL/6J	normal homeostasis/metabolism phenotype	J:200838

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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