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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tg
thyroglobulin
MGI:98733
46 phenotypes from 10 alleles in 12 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tg(Col10a1-Tg*L2263P)1Rpbh/0
Not Specified 		abnormal pelvic girdle bone morphology J:154052
decreased osteoclast cell number J:154052
increased endoplasmic reticulum stress J:154052
increased width of hypertrophic chondrocyte zone J:154052
short femur J:154052
Tg(Col10a1-Tg*L2263P)1Rpbh/Tg(Col10a1-Tg*L2263P)1Rpbh
Not Specified 		abnormal pelvic girdle bone morphology J:154052
decreased osteoclast cell number J:154052
increased endoplasmic reticulum stress J:154052
increased width of hypertrophic chondrocyte zone J:154052
short femur J:154052
Tgcog/Tgcog
AKR/J-Tgcog 		abnormal thyroid follicle morphology J:13923
abnormal thyroid follicular cell morphology J:13923
decreased circulating thyroxine level J:13923
disproportionate dwarf J:13923
enlarged thyroid gland J:13923
increased growth rate J:13923
Tgcog/Tgcog
involves: AKR/J * C57BL/6By 		abnormal myelination J:3079
anemia J:8567
decreased body weight J:3079, J:8567
decreased brain weight J:3079
decreased circulating thyroxine level J:8567
decreased circulating triiodothyronine level J:8567
decreased hematocrit J:8567
enlarged thyroid gland J:8567
increased circulating thyroid-stimulating hormone level J:8567
Tgem1(IMPC)J/Tgem1(IMPC)J
C57BL/6NJ-Tgem1(IMPC)J/Mmjax 		abnormal auditory brainstem response J:211773
abnormal coat/ hair morphology J:211773
abnormal locomotor behavior J:211773
decreased exploration in new environment J:211773
decreased locomotor activity J:211773
decreased vertical activity J:211773
improved glucose tolerance J:211773
increased bone mineral content J:211773
increased fasting circulating glucose level J:211773
increased grip strength J:211773
male infertility J:211773
prolonged RR interval J:211773
Tgm1Anu/Tgm1Anu
C57BL/6JAnu-Tgm1Anu 		decreased body size J:225105
postnatal growth retardation J:225105
Tgm1Btlr/Tgm1Btlr
C57BL/6J-Tgm1Btlr 		decreased body weight J:236668
Tgm2Btlr/Tgm2Btlr
C57BL/6J-Tgm2Btlr 		decreased body weight J:236669
Tgm3Btlr/Tgm3Btlr
C57BL/6J-Tgm3Btlr 		abnormal pelvic girdle bone morphology J:265197
decreased B cell number J:265197
decreased body fat mass J:265197
decreased body weight J:265197
decreased IgE level J:265197
decreased lean body mass J:265197
increased susceptibility to induced colitis J:265197
short femur J:265197
short tibia J:265197
Tgm3Btlr/Tgm3Btlr
C57BL/6J-Tgm3Btlr/Btlr 		decreased body size J:309727
Tgm4Btlr/Tgm4Btlr
C57BL/6J-Tgm4Btlr 		decreased B cell number J:272522
decreased B-2 B cell number J:272522
decreased body weight J:272522
increased alpha-beta T cell number J:272522
increased B-1a cell number J:272522
increased CD4-positive, alpha-beta T cell number J:272522
increased CD8-positive, alpha-beta T cell number J:272522
increased central memory CD4-positive, alpha-beta T cell number J:272522
increased fasting circulating glucose level J:272522
increased IgE level J:272522
increased macrophage cell number J:272522
TgM5Btlr/TgM5Btlr
C57BL/6J-TgM5Btlr 		increased central memory CD4-positive, alpha-beta T cell number J:272523
Tgm6Btlr/Tgm6Btlr
C57BL/6J-Tgm6Btlr 		increased alpha-beta T cell number J:272525
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory