Th Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Th
tyrosine hydroxylase
MGI:98735

39 phenotypes from 11 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Th^em1(IMPC)H/Th⁺ C57BL/6N-Th^em1(IMPC)H/H	abnormal gait	J:211773
Th^em1(IMPC)H/Th^em1(IMPC)H C57BL/6N-Th^em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Th^tm1(cre)Te/Th^tm1(cre)Te involves: 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:93194
Th^{tm1(cre/Esr1)Nat}/Th^{tm1(cre/Esr1)Nat} involves: 129 * C57BL/6	no abnormal phenotype detected	J:144315
Th^tm1.1Ich/Th^tm1.1Ich Not Specified	decreased dopamine level	J:178698
Th^tm1Gfng/Th⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:113138
Th^tm1Gfng/Th^tm1Gfng involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	prenatal lethality, complete penetrance	J:113138
Th^tm1Rpa/Th^tm1Rpa involves: 129S7/SvEvBrd * C57BL/6	abnormal heart atrium morphology	J:24347
	abnormal motor coordination/balance	J:24347
	blood vessel congestion	J:24347
	decreased body size	J:24347
	decreased body weight	J:24347
	decreased heart rate	J:24347
	dilated heart atrium	J:24347
	embryonic lethality during organogenesis, incomplete penetrance	J:24347
	fetal cardiomyocyte disarray	J:24347
	fetal cardiomyocyte vacuoles	J:24347
	lethality throughout fetal growth and development, incomplete penetrance	J:24347
	liver vascular congestion	J:24347
	postnatal lethality, complete penetrance	J:24347
	weakness	J:24347
Th^tm1Srt/Th^tm1Srt involves: 129S2/SvPas * C57BL/6J	abnormal adrenaline level	J:54692
	abnormal heart atrium morphology	J:54692
	abnormal heart development	J:54692
	abnormal noradrenaline level	J:54692
	decreased body size	J:54692
	decreased dopamine level	J:54692
	dilated heart atrium	J:54692
	embryonic lethality during organogenesis, incomplete penetrance	J:54692
	heart vascular congestion	J:54692
	ventricular hypoplasia	J:54692
	visceral vascular congestion	J:54692
Th^tm1Tna/Th⁺ B6.129-Th^tm1Tna	abnormal active avoidance behavior	J:60963
	abnormal associative learning	J:60963
	abnormal conditioned taste aversion behavior	J:60963
	abnormal cued conditioning behavior	J:60963
	abnormal learning/memory/conditioning	J:60963
	abnormal noradrenaline level	J:60963
Th^tm1Tna/Th^tm1Tna either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * ICR)	abnormal adrenaline level	J:30273
	abnormal noradrenaline level	J:30273
	abnormal ST segment	J:30273
	anoxia	J:30273
	atelectasis	J:30273
	decreased dopamine level	J:30273
	decreased heart rate	J:30273
	lethality throughout fetal growth and development, incomplete penetrance	J:30273
	neonatal lethality, complete penetrance	J:30273
	perinatal lethality, incomplete penetrance	J:30273
	respiratory failure	J:30273
Th^tm2Rpa/Th^tm2Rpa involves: 129S7/SvEvBrd * C57BL/6	abnormal heart atrium morphology	J:24347
	abnormal motor coordination/balance	J:24347
	blood vessel congestion	J:24347
	decreased body size	J:24347
	decreased body weight	J:24347
	decreased heart rate	J:24347
	dilated heart atrium	J:24347
	embryonic lethality during organogenesis, incomplete penetrance	J:24347
	fetal cardiomyocyte disarray	J:24347
	fetal cardiomyocyte vacuoles	J:24347
	lethality throughout fetal growth and development, incomplete penetrance	J:24347
	liver vascular congestion	J:24347
	postnatal lethality, complete penetrance	J:24347
	weakness	J:24347
Th^tm4.1Rpa/Th^tm4.1Rpa Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * SJL	abnormal eye electrophysiology	J:185955
	abnormal eye physiology	J:185955
	abnormal vision	J:185955
	decreased dopamine level	J:185955
Th^tm5Rpa/Th^tm5Rpa involves: 129S4/SvJaeSor * C57BL/6	prenatal lethality, complete penetrance	J:110806

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