About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Thrb
thyroid hormone receptor beta
MGI:98743
47 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ncoa1tm1Bwo/Ncoa1tm1Bwo
Thrbtm1Olc/Thrbtm1Olc
B6.129-Ncoa1tm1Bwo Thrbtm1Olc 		abnormal response/metabolism to endogenous compounds J:126521
increased circulating thyroid-stimulating hormone level J:126521
increased circulating thyroxine level J:126521
increased circulating triiodothyronine level J:126521
Thratm1Jas/Thra+
Thrbtm1Olc/Thrbtm1Olc
involves: 129/Sv * 129S1/Sv * 129X1/SvJ 		postnatal growth retardation J:52829
Thratm1Jas/Thratm1Jas
Thrbtm1Olc/Thrbtm1Olc
involves: 129/Sv * 129S1/Sv * 129X1/SvJ 		abnormal long bone epiphyseal plate morphology J:52829
abnormal small intestine morphology J:52829
abnormal thyroid follicle morphology J:52829
decreased body weight J:52829
decreased small intestinal villus size J:52829
delayed intestine development J:52829
delayed skeletal maturation J:52829
increased circulating thyroid-stimulating hormone level J:52829
increased circulating thyroxine level J:52829
increased triiodothyronine level J:52829
postnatal growth retardation J:52829
premature death J:52829
thyroid gland hyperplasia J:52829
Thratm1Ven/Thra+
Thrbtm1Df/Thrbtm1Df
B6.129-Thratm1Ven Thrbtm1Df 		increased or absent threshold for auditory brainstem response J:73382
Thratm1Ven/Thratm1Ven
Thrbtm1Df/Thrb+
B6.129-Thratm1Ven Thrbtm1Df 		normal hearing/vestibular/ear phenotype J:73382
Thratm1Ven/Thratm1Ven
Thrbtm1Df/Thrbtm1Df
B6.129-Thratm1Ven Thrbtm1Df 		abnormal auditory brainstem response J:73382
abnormal pituitary hormone level J:117324
abnormal sperm motility J:117324
decreased body weight J:117324
decreased follicle stimulating hormone level J:117324
decreased growth hormone level J:117324
decreased luteinizing hormone level J:117324
decreased prolactin level J:117324
decreased testis weight J:117324
female infertility J:73382
increased thyroid-stimulating hormone level J:117324
Thratm1Ven/Thratm1Ven
Thrbtm1Df/Thrbtm1Df
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		increased circulating thyroid-stimulating hormone level J:95391
increased circulating thyroxine level J:95391
increased circulating triiodothyronine level J:95391
normal neoplasm J:95391
small pituitary gland J:95391
Thratm1Ven/Thratm1Ven
Thrbtm1Df/Thrbtm1Df
involves: 129P2/OlaHsd * 129S1/Sv * BALB/c * C57BL/6J 		abnormal cochlear inner hair cell physiology J:73382
abnormal cochlear outer hair cell physiology J:73382
abnormal organ of Corti morphology J:73382
abnormal pillar cell morphology J:73382
abnormal tectorial membrane morphology J:73382
abnormal tectorial membrane striated-sheet matrix morphology J:73382
decreased body size J:73382
decreased cochlear outer hair cell electromotility J:73382
decreased endocochlear potential J:73382
delayed inner ear development J:73382
enlarged tectorial membrane J:73382
female infertility J:73382
increased susceptibility to xenobiotic induced morbidity/mortality J:73382
Thratm2Ven/Thra+
Thrbtm1Df/Thrbtm1Df
involves: 129P2/OlaHsd * BALB/c * C57BL/6J 		normal hearing/vestibular/ear phenotype J:118402
postnatal growth retardation J:118402
Thratm2Ven/Thratm2Ven
Thrbtm1Df/Thrbtm1Df
involves: 129P2/OlaHsd * BALB/c * C57BL/6J 		abnormal thyroid follicle morphology J:118402
abnormal thyroid hormone level J:118402
decreased circulating thyroxine level J:118402
decreased circulating triiodothyronine level J:118402
normal hearing/vestibular/ear phenotype J:118402
postnatal growth retardation J:118402
Thratm3Ven/Thra+
Thrbtm1Df/Thrb+
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6NCrl 		abnormal postnatal growth J:100290
decreased body weight J:100290
Thratm3Ven/Thra+
Thrbtm1Df/Thrbtm1Df
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6NCrl 		decreased body weight J:100290
Thratm3Ven/Thratm3Ven
Thrbtm1Df/Thrbtm1Df
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6NCrl 		preweaning lethality, complete penetrance J:100290
Thrbtm5Few/Thrb+
involves: 129 * C57BL/6 		increased circulating thyroxine level J:100929
increased thyroid gland weight J:100929
Thrbtm5Few/Thrbtm5Few
involves: 129 * C57BL/6 		increased circulating thyroid-stimulating hormone level J:100929
increased circulating thyroxine level J:100929
increased circulating triiodothyronine level J:100929
increased thyroid gland weight J:100929
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory