Timp1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Timp1
tissue inhibitor of metalloproteinase 1
MGI:98752

3 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Timp1^tm1Pds/Y involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	abnormal blood vessel physiology	J:103082
Mmp2^tm1Ito/Mmp2^tm1Ito Timp1^tm1Pds/Timp1^tm1Pds either: (involves: 129S4/SvJae) or (involves: C57BL/6)	decreased susceptibility to bacterial infection	J:94836
Mmp3^tm1Mrl/Mmp3^tm1Mrl Timp1^tm1Pds/Timp1^tm1Pds involves: C57BL/6	decreased susceptibility to bacterial infection	J:94836
Mmp7^tm1Lmm/Mmp7^tm1Lmm Timp1^tm1Pds/Timp1^tm1Pds involves: 129S4/SvJae	decreased susceptibility to bacterial infection	J:94836
Mmp9^tm1Tvu/Mmp9^tm1Tvu Timp1^tm1Pds/Timp1^tm1Pds involves: 129S4/SvJae * 129S6/SvEvTac	normal immune system phenotype	J:94836
Mmp12^tm1Sds/Mmp12^tm1Sds Timp1^tm1Pds/Timp1^tm1Pds either: (involves: 129S4/SvJae) or (involves: C57BL/6)	decreased susceptibility to bacterial infection	J:94836

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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