Timp3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Timp3
tissue inhibitor of metalloproteinase 3
MGI:98754

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp2^tm1Ito/Mmp2^tm1Ito Timp3^tm1Osya/Timp3^tm1Osya involves: 129P2/OlaHsd * C57BL/6	abnormal abdominal aorta morphology	J:193744
	abnormal aorta wall morphology	J:193744
	aortitis	J:193744
	increased susceptibility to induced aneurysm formation	J:193744
	increased susceptibility to induced morbidity/mortality	J:193744
Timp3^tm1Rkho/Timp3^tm1Rkho Tnf^tm1Gkl/Tnf^tm1Gkl involves: 129 * 129S/SvEv * C57BL/6	decreased heart ventricle muscle contractility	J:112033
	dilated heart left ventricle	J:112033
	increased neutrophil cell number	J:112033

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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