Tlx1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tlx1
T cell leukemia, homeobox 1
MGI:98769

10 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tlx1^{tm1.1(cre/ERT2)Rygo}/Tlx1^{tm1.1(cre/ERT2)Rygo} involves: C57BL/6 * C57BL/6JJcl * C57BL/6NSlc	absent spleen	J:217489
Tlx1^tm1Sjk/Tlx1^tm1Sjk involves: 129S2/SvPas	abnormal spleen development	J:17695
	abnormal spleen mesenchyme morphology	J:17695
	absent spleen	J:17695
	normal embryo phenotype	J:17695
	increased leukocyte cell number	J:17695
	increased lymphocyte cell number	J:17695
	increased neutrophil cell number	J:17695
	increased number of Howell-Jolly bodies	J:17695
	normal nervous system phenotype	J:17695
Tlx1^tm1Thr/Tlx1^tm1Thr involves: 129P2/OlaHsd * MF1	abnormal spleen development	J:28700
	absent spleen	J:28700
	increased splenocyte apoptosis	J:28700

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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