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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnnc1
troponin C, cardiac/slow skeletal
MGI:98779
33 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tnnc1em1(IMPC)J/Tnnc1+
C57BL/6NJ-Tnnc1em1(IMPC)J/Mmjax 		abnormal embryo size J:211773
impaired righting response J:211773
limb grasping J:211773
Tnnc1em1(IMPC)J/Tnnc1em1(IMPC)J
C57BL/6NJ-Tnnc1em1(IMPC)J/Mmjax 		embryonic lethality prior to tooth bud stage J:211773
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Tnnc1tm1.1Jrpi/Tnnc1+
involves: 129S6/SvEvTac * C57BL/6 		abnormal heart echocardiography feature J:274007
abnormal heart left ventricle pressure J:274007
abnormal myocardial fiber morphology J:274007
abnormal myocardial fiber physiology J:274007
cardiac interstitial fibrosis J:274007
cardiomyopathy J:274007
decreased heart weight J:274007
heart right ventricle hypertrophy J:274007
increased cardiac stroke volume J:274007
increased heart atrium size J:274007
papillary muscle hypertrophy J:274007
thick ventricular wall J:274007
Tnnc1tm1.1Jrpi/Tnnc1tm1.1Jrpi
involves: 129S6/SvEvTac * C57BL/6 		abnormal adrenal gland morphology J:249978
abnormal cardiac muscle contractility J:249978
abnormal cardiac muscle relaxation J:249978
abnormal cardiovascular system physiology J:274007
abnormal forebrain morphology J:249978
abnormal heart echocardiography feature J:249978, J:274007
abnormal heart left ventricle pressure J:274007
abnormal heart morphology J:274007
abnormal myocardial fiber physiology J:274007
abnormal sympathetic nervous system physiology J:249978
behavioral despair J:249978
cardiac interstitial fibrosis J:274007
cardiomyopathy J:274007
decreased cardiac muscle relaxation J:274007
decreased heart rate J:249978
decreased heart weight J:274007
heart left ventricle hypertrophy J:274007
heart right ventricle hypertrophy J:274007
increased anxiety-related response J:249978
increased cardiac muscle contractility J:274007
increased cardiac stroke volume J:274007
increased heart atrium size J:274007
increased heart left atrium weight J:274007
myocardial fiber disarray J:274007
papillary muscle hypertrophy J:274007
thick ventricular wall J:274007
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory