Tpi1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tpi1
triosephosphate isomerase 1
MGI:98797

23 phenotypes from 8 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tpi1^a-M1Neu/Tpi1⁺ involves: 101/El * C3H/El	no abnormal phenotype detected	J:14635
Tpi1^a-M1Neu/Tpi1^a-M1Neu involves: 101/El * C3H/El	embryonic lethality between implantation and somite formation, complete penetrance	J:14635
Tpi1^a-M2Neu/Tpi1⁺ involves: 101/El * C3H/El	no abnormal phenotype detected	J:14635
Tpi1^a-M2Neu/Tpi1^a-M2Neu involves: 101/El * C3H/El	embryonic lethality between implantation and somite formation, complete penetrance	J:14635
Tpi1^a-M3Neu/Tpi1⁺ involves: 101/El * C3H/El	no abnormal phenotype detected	J:14635
Tpi1^a-M3Neu/Tpi1^a-M3Neu involves: 101/El * C3H/El	embryonic lethality between implantation and somite formation, complete penetrance	J:14635
Tpi1^a-M4Neu/Tpi1⁺ involves: 101/El * C3H/El	no abnormal phenotype detected	J:14635
Tpi1^a-M4Neu/Tpi1^a-M4Neu involves: 101/El * C3H/El	embryonic lethality between implantation and somite formation, complete penetrance	J:14635
Tpi1^a-M5Neu/Tpi1^a-M5Neu involves: 101/El * C3H/El	no abnormal phenotype detected	J:11280
Tpi1^a-m6Neu/Tpi1⁺ involves: 101/El * C3H/El	abnormal enzyme/coenzyme activity	J:163223
Tpi1^a-m6Neu/Tpi1^a-m6Neu involves: 101/El * C3H/El	abnormal enzyme/coenzyme activity	J:163223
	decreased hematocrit	J:163223
	decreased hemoglobin content	J:163223
	decreased mean corpuscular hemoglobin concentration	J:163223
	hemolytic anemia	J:163223
	increased mean corpuscular volume	J:163223
	increased spleen weight	J:163223
Tpi1^rbc19/Tpi1^rbc19 SJL-Tpi1^rbc19	abnormal erythrocyte physiology	J:263104
	abnormal erythropoiesis	J:263104
	abnormal homeostasis	J:263104
	abnormal spleen red pulp morphology	J:263104
	decreased erythrocyte cell number	J:263104
	decreased hematocrit	J:263104
	enlarged spleen	J:263104
	hemolytic anemia	J:263104
	increased circulating bilirubin level	J:263104
	increased mean corpuscular hemoglobin	J:263104
	macrocytic anemia	J:263104
	macrocytosis	J:263104
	normal nervous system phenotype	J:263104
	polychromatophilia	J:263104
	reticulocytosis	J:263104
Tpi1^{tm1a(EUCOMM)Wtsi}/Tpi1⁺ B6JTyr;B6N-Tpi1^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body weight	J:175295

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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