Tpo Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tpo
thyroid peroxidase
MGI:98813

44 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tpo^em1(IMPC)H/Tpo⁺ C57BL/6NTac-Tpo^em1(IMPC)H/H	decreased circulating glucose level	J:211773
	improved glucose tolerance	J:211773
	increased mean platelet volume	J:211773
Tpo^em1(IMPC)H/Tpo^em1(IMPC)H C57BL/6NTac-Tpo^em1(IMPC)H/H	abnormal coat/ hair morphology	J:211773
	abnormal forelimb morphology	J:211773
	abnormal gait	J:211773
	abnormal hindlimb morphology	J:211773
	abnormal startle reflex	J:211773
	decreased exploration in new environment	J:211773
	impaired righting response	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating iron level	J:211773
	limb grasping	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	tremors	J:211773
Tpo^R479C/Tpo^R479C involves: ICR	abnormal enzyme/coenzyme activity	J:112930
	abnormal thyroid follicle morphology	J:112930
	abnormal thyroid follicular cell morphology	J:112930
	decreased body size	J:112930
	decreased body weight	J:112930
	decreased erythrocyte cell number	J:112930
	decreased hematocrit	J:112930
	disproportionate dwarf	J:112930
	enlarged thyroid gland	J:112930
	exophthalmos	J:112930
	increased circulating thyroid-stimulating hormone level	J:112930
	premature death	J:112930
	prominent forehead	J:112930
	small spleen	J:112930
Tpo^tee-2J/Tpo^tee-2J B6.Cg-Tpo^tee-2J H2^g7/GrsrJ	abnormal cochlea morphology	J:202956
	abnormal tectorial membrane morphology	J:202956
	abnormal thyroid follicle morphology	J:202956
	abnormal thyroid gland development	J:202956
	abnormal thyroid gland morphology	J:202956
	abnormal thyroid gland physiology	J:202956
	decreased activity of thyroid gland	J:202956
	delayed inner ear development	J:202956
	increased or absent threshold for auditory brainstem response	J:202956
	proportional dwarf	J:202956
	small thyroid gland	J:202956
Tpo^tee-2J/Tpo^tee-2J C3.B6(NOD)-Tpo^tee-2J/Kjn	increased or absent threshold for auditory brainstem response	J:202956
Tpo^tee-2J/Tpo^tee-2J C3.B6(NOD)-Tpo^tee-2J/Kjn	proportional dwarf	J:202956
Tpo^tee/Tpo^tee C57BL/6J-Tpo^tee/GrsrJ	abnormal cochlea morphology	J:202956
	abnormal femur morphology	J:202956
	abnormal tectorial membrane morphology	J:202956
	abnormal thyroid follicle morphology	J:202956
	abnormal thyroid gland development	J:202956
	abnormal thyroid gland morphology	J:202956
	abnormal thyroid gland physiology	J:202956
	decreased activity of thyroid gland	J:202956
	delayed inner ear development	J:202956
	increased or absent threshold for auditory brainstem response	J:202956
	proportional dwarf	J:202956
	small thyroid gland	J:202956
	normal vision/eye phenotype	J:202956

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