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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kdm3a
lysine (K)-specific demethylase 3A
MGI:98847
56 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kdm3aem1(IMPC)Mbp/Kdm3aem1(IMPC)Mbp
C57BL/6N-Kdm3aem1(IMPC)Mbp/MbpMmucd 		abnormal behavior J:211773
abnormal bone structure J:211773
abnormal kidney morphology J:211773
abnormal skin morphology J:211773
decreased anxiety-related response J:211773
decreased bone mineral content J:211773
decreased prepulse inhibition J:211773
decreased thigmotaxis J:211773
enlarged spleen J:211773
eye hemorrhage J:211773
hyperactivity J:211773
impaired glucose tolerance J:211773
male infertility J:211773
small kidney J:211773
small spleen J:211773
Kdm3aGt(YHA186)Byg/Kdm3aGt(YHA186)Byg
involves: 129P2/OlaHsd 		obese J:147295
Kdm3aGt(YHA186)Byg/Kdm3aGt(YHA186)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal acrosome assembly J:127121
abnormal seminiferous tubule morphology J:127121
abnormal sperm head morphology J:127121
abnormal spermatid morphology J:127121
abnormal spermatogenesis J:127121
abnormal spermiogenesis J:127121
asthenozoospermia J:127121
male infertility J:127121
oligozoospermia J:127121
normal reproductive system phenotype J:127121
small testis J:127121
Kdm3atm1.1Jsak/Kdm3atm1.1Jsak
involves: C57BL/6 * CBA 		abnormal white adipose tissue morphology J:158258
impaired adaptive thermogenesis J:158258
increased circulating cholesterol level J:158258
increased circulating glucose level J:158258
increased circulating insulin level J:158258
increased circulating leptin level J:158258
increased circulating triglyceride level J:158258
increased epididymal fat pad weight J:158258
increased fat cell size J:158258
increased respiratory quotient J:158258
increased retroperitoneal fat pad weight J:158258
increased susceptibility to weight gain J:158258
increased white adipose tissue amount J:158258
insulin resistance J:158258
obese J:158258
Kdm3atm1.1Yzha/Kdm3atm1.1Yzha
B6.129P2-Kdm3atm1.1Yzha 		abnormal brown adipose tissue morphology J:147295
abnormal brown adipose tissue physiology J:147295
abnormal muscle morphology J:147295
abnormal muscle physiology J:147295
abnormal spermatogenesis J:147295
normal behavior/neurological phenotype J:147295
decreased oxygen consumption J:147295
hepatic steatosis J:147295
normal homeostasis/metabolism phenotype J:147295
hyperlipidemia J:147295
impaired adaptive thermogenesis J:147295
increased brown adipose tissue amount J:147295
increased circulating cholesterol level J:147295
increased circulating free fatty acids level J:147295
increased circulating triglyceride level J:147295
increased percent body fat/body weight J:147295
increased susceptibility to diet-induced obesity J:147295
increased white fat cell lipid droplet size J:147295
obese J:147295
Kdm3atm1Jxu/Kdm3atm1Jxu
involves: 129S6/SvEvTac * C57BL/6 		abnormal spermatid morphology J:159956
abnormal spermatogenesis J:159956
abnormal spermiogenesis J:159956
decreased testis weight J:159956
increased male germ cell apoptosis J:159956
male infertility J:159956
oligozoospermia J:159956
small testis J:159956
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory