About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tshr
thyroid stimulating hormone receptor
MGI:98849
68 phenotypes from 5 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Tshrhyt-2J/Tshrhyt-2J
B6;129P3-Tshrhyt-2J/GrsrJ 		abnormal cone electrophysiology J:213054
abnormal thyroid follicle morphology J:213054
decreased b-wave amplitude J:213054
decreased body weight J:213054
decreased circulating thyroxine level J:213054
increased or absent threshold for auditory brainstem response J:213054
increased thyrotroph cell number J:213054
maternal effect J:213054
normal reproductive system phenotype J:213054
Tshrhyt-3J/Tshrhyt-3J
CByJ;CXB10-Tshrhyt-3J/GrsrJ 		decreased activity of thyroid gland J:210510
lethality at weaning, incomplete penetrance J:210510
premature death J:210510
prenatal lethality, incomplete penetrance J:210510
proportional dwarf J:210510
reduced female fertility J:210510
reduced male fertility J:210510
Tshrhyt-3J/Tshrhyt-3J
CXB10/HiAJ-Tshrhyt-3J/GrsrJ 		decreased activity of thyroid gland J:210510
increased or absent threshold for auditory brainstem response J:210510
lethality at weaning, incomplete penetrance J:210510
premature death J:210510
prenatal lethality, incomplete penetrance J:210510
proportional dwarf J:210510
reduced female fertility J:210510
reduced male fertility J:210510
Tshrhyt/Tshrhyt
CBy.RF-Tshrhyt/J 		abnormal bone mineralization J:130062
abnormal bone remodeling J:130062
abnormal bone trabecula morphology J:130062
abnormal epiphyseal plate morphology J:130062
abnormal frequency of paradoxical sleep J:72929
abnormal long bone epiphyseal plate proliferative zone J:130062
abnormal organ of Corti morphology J:110962
abnormal outer hair cell stereociliary bundle morphology J:110962
abnormal tectorial membrane morphology J:110962
abnormal uterine environment J:72929
absent estrous cycle J:72929
circling J:85902
deafness J:111112
decreased activity of thyroid gland J:130062
decreased B cell number J:111014
decreased body length J:85902
decreased body size J:85902
decreased body weight J:85902
decreased bone mineral density of caudal vertebrae J:130062
decreased bone mineral density of femur J:130062
decreased bone volume J:130062
decreased circulating progesterone level J:72929
decreased cochlear outer hair cell number J:110962
decreased compact bone thickness J:130062
decreased distortion product otoacoustic emission amplitude J:110962
decreased dopaminergic neuron number J:85902
decreased femur compact bone thickness J:130062
decreased outer hair cell stereocilia number J:110962
decreased superovulation rate J:72929
decreased thyroxine level J:130062
delayed bone ossification J:130062
delayed endochondral bone ossification J:130062
impaired adaptive thermogenesis J:139995
impaired luteinization J:72929
increased or absent distortion product otoacoustic emission threshold J:110962
increased or absent threshold for auditory brainstem response J:110962, J:111112
increased pro-B cell number J:111014
increased stereotypic behavior J:85902
increased thyroid-stimulating hormone level J:130062
short limbs J:130062
unidirectional circling J:85902
Tshrhyt/Tshrhyt
involves: BALB/cByJ * RF/J 		abnormal thyroid follicle morphology J:6479
anemia J:6479
decreased body size J:6479
decreased circulating thyroxine level J:6479
female infertility J:6479
increased circulating cholesterol level J:6479
increased circulating thyroid-stimulating hormone level J:6479
male infertility J:6479
Tshrm1Btlr/Tshrm1Btlr
C57BL/6J-Tshrm1Btlr 		decreased body weight J:221489
Tshrtm1Rmar/Tshrtm1Rmar
involves: 129S1/Sv 		abnormal thyroid follicle morphology J:168249
small thyroid gland J:168249
Tshrtm1Rmar/Tshrtm1Rmar
involves: 129S1/Sv * C57BL/6J 		abnormal thyroid follicle morphology J:80513
abnormal thyroid gland physiology J:80513
abnormal thyroid hormone level J:80513
decreased activity of thyroid gland J:80513
decreased circulating levels of thyroid hormone J:80513
decreased circulating thyroxine level J:80513
decreased circulating triiodothyronine level J:80513
increased circulating thyroid-stimulating hormone level J:80513
iodide oxidation defect J:80513
lethality at weaning, complete penetrance J:80513
postnatal growth retardation J:80513
reduced fertility J:80513
small thyroid gland J:80513
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory