Ttr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ttr
transthyretin
MGI:98865

14 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(TTR)#Jbux/0 involves: C57BL/6 * DBA/2	abnormal protein level	J:68458
Tg(TTR)#Jbux/0 involves: C57BL/6 * DBA/2	amyloidosis	J:68458
Tg(TTRL55P)#Jbux/0 involves: C57BL/6 DBA/2	normal homeostasis/metabolism phenotype	J:68458
Ttr^em1(IMPC)H/Ttr^em1(IMPC)H C57BL/6NTac-Ttr^em1(IMPC)H/H	decreased locomotor activity	J:211773
Ttr^tm1.1Smoc/? involves: C57BL/6J * C57BL/6N	amyloidosis	J:257096
	increased opacity of vitreous body	J:257096
	vitreous body deposition	J:257096
Ttr^tm1Kymm/Ttr^tm1Kymm B6.Cg-Ttr^tm1Kymm	abnormal circulating protein level	J:146510
	abnormal retinol level	J:146510
	decreased circulating thyroxine level	J:146510
	decreased circulating triiodothyronine level	J:146510
Ttr^tm1Wsb/Ttr⁺ involves: 129S/SvEv * MF1	decreased circulating thyroxine level	J:4183
Ttr^tm1Wsb/Ttr⁺ involves: 129S/SvEv * MF1	decreased circulating triiodothyronine level	J:4183
Ttr^tm1Wsb/Ttr^tm1Wsb involves: 129S/SvEv	abnormal blood homeostasis	J:22576
	decreased circulating thyroxine level	J:22576
	normal vision/eye phenotype	J:73380
Ttr^tm1Wsb/Ttr^tm1Wsb involves: 129S/SvEv * MF1	abnormal circulating protein level	J:4183
	abnormal retinol level	J:4183
	abnormal retinol metabolism	J:4183
	decreased circulating levels of thyroid hormone	J:4183
	decreased circulating thyroxine level	J:4183
	decreased circulating triiodothyronine level	J:4183

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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