About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tuba1a
tubulin, alpha 1A
MGI:98869
43 phenotypes from 6 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Tuba1aem1(IMPC)Bay/Tuba1aem1(IMPC)Bay
C57BL/6N-Tuba1aem1(IMPC)Bay/BayMmucd 		abnormal embryo size J:211773
abnormal facial morphology J:211773
edema J:211773
hemorrhage J:211773
preweaning lethality, incomplete penetrance J:211773
Tuba1aem1Rstot/Tuba1aem1Rstot
involves: C57BL/6J * C57BL/6N 		abnormal basal ganglion morphology J:278765
abnormal cortical intermediate zone morphology J:278765
abnormal cortical plate morphology J:278765
abnormal neuron physiology J:278765
abnormal spine curvature J:278765
abnormal telencephalon development J:278765
abnormal third ventricle morphology J:278765
cleft palate J:278765
edema J:278765
enlarged lateral ventricles J:278765
enlarged third ventricle J:278765
hemorrhage J:278765
increased cortical ventricular zone thickness J:278765
increased neuronal precursor proliferation J:278765
preweaning lethality, complete penetrance J:278765
Tuba1aem1Rstot/Tuba1aquas
involves: C57BL/6J * C57BL/6N 		abnormal basal ganglion morphology J:278765
abnormal cerebral cortex morphology J:278765
abnormal cortical intermediate zone morphology J:278765
abnormal spine curvature J:278765
cleft palate J:278765
enlarged lateral ventricles J:278765
enlarged third ventricle J:278765
preweaning lethality, complete penetrance J:278765
Tuba1aem2Rstot/Tuba1aem2Rstot
involves: C57BL/6J * C57BL/6N 		abnormal basal ganglion morphology J:278765
abnormal cortical intermediate zone morphology J:278765
abnormal cortical plate morphology J:278765
abnormal spine curvature J:278765
abnormal telencephalon development J:278765
abnormal third ventricle morphology J:278765
cleft palate J:278765
edema J:278765
enlarged lateral ventricles J:278765
enlarged third ventricle J:278765
hemorrhage J:278765
increased cortical ventricular zone thickness J:278765
preweaning lethality, complete penetrance J:278765
Tuba1aJna/Tuba1a+
involves: BALB/cAnN * C3H/HeH 		abnormal Ammon gyrus morphology J:117881
abnormal auditory cortex morphology J:117881
abnormal cerebral cortex morphology J:117881
abnormal dentate gyrus morphology J:117881
abnormal hippocampal mossy fiber morphology J:117881
abnormal hippocampus morphology J:117881
abnormal hippocampus pyramidal cell layer J:117881
abnormal nest building behavior J:117881
abnormal somatosensory cortex morphology J:117881
abnormal spatial working memory J:117881
abnormal visual cortex morphology J:117881
decreased anxiety-related response J:117881
decreased body weight J:117881
decreased hippocampus pyramidal cell number J:117881
hyperactivity J:117881
impaired neuronal migration J:117881
Tuba1aquas/Tuba1aquas
involves: C57BL/6J 		abnormal cerebral cortex morphology J:278765
abnormal neuron physiology J:278765
abnormal neuronal migration J:278765
abnormal neuronal precursor cell number J:278765
abnormal spine curvature J:278765
decreased neuronal precursor proliferation J:278765
enlarged lateral ventricles J:278765
enlarged third ventricle J:278765
increased neuron apoptosis J:278765
increased neuronal precursor proliferation J:278765
Tuba1aRgsc1736/Tuba1a+
C3.B6-Tuba1aRgsc1736 		abnormal cerebral cortex pyramidal cell morphology J:180670
abnormal dendrite morphology J:180670
abnormal neuron morphology J:180670
abnormal response to novel object J:180670
decreased anxiety-related response J:180670
increased locomotor activity J:180670
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory