U2af1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

U2af1
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
MGI:98884

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Runx1^tm3Spe/Runx1^tm3Spe U2af1^tm1.1Hev/U2af1⁺ Tg(Mx1-cre)1Cgn/0 involves: 129S4/SvJae * 129S6/SvEvTac * BALB/c * C57BL/6 * CBA/J	abnormal blood cell morphology	J:267082
	abnormal erythroid lineage cell morphology	J:267082
	abnormal myeloid cell morphology	J:267082
	increased incidence of tumors by chemical induction	J:267082
	increased myeloid cell number	J:267082
	increased susceptibility to induced morbidity/mortality	J:267082
	normal mortality/aging	J:267082
	thrombocytopenia	J:267082

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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