Vim Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vim
vimentin
MGI:98932

39 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(VimR113C)1Tmm/0 B6.CBA-Tg(VimR113C)1Tmm	abnormal cell morphology	J:145782
	abnormal lens fiber morphology	J:145782
	cataract	J:145782
	disorganized secondary lens fibers	J:145782
	ruptured lens capsule	J:145782
Vim^tm1Cba/Vim^tm1Cba involves: 129S2/SvPas	abnormal astrocyte morphology	J:78341
	abnormal cell migration	J:118721
	abnormal cell morphology	J:118721
	abnormal cell physiology	J:118721
	abnormal cerebellar Purkinje cell layer	J:79046
	abnormal cerebellum morphology	J:79046
	abnormal locomotor behavior	J:79046
	abnormal motor learning	J:79046
	abnormal Purkinje cell dendrite morphology	J:79046
	abnormal Purkinje cell morphology	J:79046
	abnormal vasoconstriction	J:43049
	abnormal vasodilation	J:43049
	normal cardiovascular system phenotype	J:43049
	decreased mean systemic arterial blood pressure	J:43049
	decreased Purkinje cell number	J:79046
	normal embryo phenotype	J:21588
	hyperactivity	J:79046
	impaired balance	J:79046
	impaired coordination	J:79046
	increased anxiety-related response	J:79046
	increased circulating creatinine level	J:43049
	increased susceptibility to induced morbidity/mortality	J:43049
	normal nervous system phenotype	J:168641
	Purkinje cell degeneration	J:79046
	normal reproductive system phenotype	J:21588
	normal respiratory system phenotype	J:43049
Vim^tm1Cba/Vim^tm1Cba involves: 129S2/SvPas * C57BL/6	abnormal astrocyte morphology	J:125659
	abnormal blood vessel morphology	J:129405
	abnormal cellular extravasation	J:129405
	abnormal leukocyte adhesion	J:129405
	abnormal leukocyte migration	J:129405
	abnormal leukocyte tethering or rolling	J:129405
	normal cellular phenotype	J:125280, J:125659
	normal homeostasis/metabolism phenotype	J:125280
	normal immune system phenotype	J:125280
	normal nervous system phenotype	J:125659
Vim^tm2Cba/Vim^tm2Cba involves: 129S2/SvPas	abnormal angiogenesis	J:103293
	abnormal cell migration	J:118721
	abnormal cell morphology	J:118721
	abnormal cell physiology	J:118721
	normal embryo phenotype	J:21588
	normal reproductive system phenotype	J:21588

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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