Vldlr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vldlr
very low density lipoprotein receptor
MGI:98935

48 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vldlr^em1(IMPC)Mbp/Vldlr^em1(IMPC)Mbp C57BL/6N-Vldlr^em1(IMPC)Mbp/MbpMmucd	abnormal behavior	J:211773
	abnormal heart morphology	J:211773
	abnormal spleen morphology	J:211773
	blind uterus	J:211773
	decreased anxiety-related response	J:211773
	decreased thigmotaxis	J:211773
	enlarged heart	J:211773
	hyperactivity	J:211773
	increased exploration in new environment	J:211773
Vldlr^m1Btlr/Vldlr^m1Btlr C57BL/6J-Vldlr^m1Btlr	abnormal retina morphology	J:176337
	abnormal retina outer nuclear layer morphology	J:176337
	abnormal retina photoreceptor morphology	J:176337
	abnormal retina pigment epithelium morphology	J:176337
	abnormal retina pigmentation	J:176337
	abnormal retina vasculature morphology	J:176337
	retina photoreceptor degeneration	J:176337
Vldlr^m1Btlr/Vldlr^tm1Her involves: 129S7/SvEvBrd * C57BL/6J	abnormal retina vasculature morphology	J:176337
Vldlr^m2Btlr/Vldlr^m2Btlr C57BL/6J-Vldlr^m2Btlr	decreased total retina thickness	J:264645
	eye lesions	J:264645
	thin retina outer nuclear layer	J:264645
Vldlr^rnv4/Vldlr^rnv4 B6;BKS-Vldlr^rnv4/BocJ	abnormal cone electrophysiology	J:274099
	abnormal retina blood vessel pattern	J:274099
	abnormal retina vasculature morphology	J:274099
	abnormal rod electrophysiology	J:274099
	alopecia	J:274099
	decreased body size	J:274099
Vldlr^tm1Her/Vldlr^tm1Her B6;129S7-Vldlr^tm1Her/J	abnormal retina morphology	J:128315, J:132497
	abnormal retina neuronal layer morphology	J:128315
	abnormal retina pigment epithelium morphology	J:128315, J:132497
	choroidal neovascularization	J:132497
	decreased retina photoreceptor cell number	J:128315, J:132497
	disorganized retina inner nuclear layer	J:128315
	retina neovascularization	J:128315, J:132497
	retina outer nuclear layer degeneration	J:132497
	retina photoreceptor degeneration	J:132497
	thin retina outer nuclear layer	J:128315, J:132497
Vldlr^tm1Her/Vldlr^tm1Her involves: 129S7/SvEvBrd	abnormal brain development	J:55691
	abnormal brain morphology	J:55691
	abnormal cerebellum morphology	J:55691
	abnormal contextual conditioning behavior	J:79593
	abnormal cued conditioning behavior	J:79593
	abnormal long-term potentiation	J:79593
	hyperactivity	J:79593
	impaired synaptic plasticity	J:79593
	reduced cerebellar foliation	J:55691
	reduced long-term potentiation	J:79593
	small cerebellum	J:55691
Vldlr^tm1Her/Vldlr^tm1Her involves: 129S7/SvEvBrd * C57BL/6	abnormal ocular fundus morphology	J:114757
	choroidal neovascularization	J:114757
	normal homeostasis/metabolism phenotype	J:117317
	increased circulating cholesterol level	J:117317
	increased circulating triglyceride level	J:117317
	pathological neovascularization	J:114757
Vldlr^tm1Her/Vldlr^tm1Her involves: 129S7/SvEvBrd * C57BL/6J	decreased body size	J:28591
	decreased body weight	J:28591
	decreased epididymal fat pad weight	J:28591
	normal homeostasis/metabolism phenotype	J:28591
Vldlr^tm1Lex/Vldlr^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	increased vascular permeability	J:181399
Vldlr^tm1Lex/Vldlr^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	retina neovascularization	J:181399

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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