Vwf Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vwf
Von Willebrand factor
MGI:98941

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adamts13^tm1Dgi/Adamts13^tm1Dgi Vwf^tm1Wgr/Vwf^tm1Wgr B6.129-Adamts13^tm1Dgi Vwf^tm1Wgr	decreased susceptibility to induced thrombosis	J:133469
	normal hematopoietic system phenotype	J:133469
	normal homeostasis/metabolism phenotype	J:133469
Adamts13^tm1Dgi/Adamts13^tm1Dgi Vwf^tm1Wgr/Vwf^tm1Wgr involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CASA/Rk	abnormal platelet morphology	J:133469
	decreased physiological sensitivity to xenobiotic	J:133469
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:133469
Fga^tm1Jld/Fga^tm1Jld Vwf^tm1Wgr/Vwf^tm1Wgr involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6J	abnormal blood coagulation	J:63750
	postnatal lethality, incomplete penetrance	J:63750
Itga2b^tm1Tlr/Itga2b^tm1Tlr Vwf^tm1.1Diac/Vwf^tm1.1Diac involves: 129S1/Sv * 129X1/SvJ	normal homeostasis/metabolism phenotype	J:181672
Ldlr^tm1Her/Ldlr^tm1Her Vwf^tm1Wgr/Vwf^tm1Wgr B6.129S-Vwf^tm1Wgr Ldlr^tm1Her	decreased susceptibility to atherosclerosis	J:106677
	impaired leukocyte tethering or rolling	J:106677
Vwf^{tm3.1(VWF)Diac}/Vwf^{tm3.1(VWF)Diac} Not Specified	impaired blood coagulation	J:220792
Vwf^{tm3.1(VWF)Diac}/Vwf^{tm3.1(VWF)Diac} Not Specified	increased bleeding time	J:220792

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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