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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Wnt3a
wingless-type MMTV integration site family, member 3A
MGI:98956
68 phenotypes from 6 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Krj/Emx1+
Wnt3atm2Eag/Wnt3a+
involves: 129S2/SvPas 		abnormal cerebral cortex morphology J:104373
abnormal suckling behavior J:104373
absent Cajal-Retzius cell J:104373
absent choroid plexus J:104373
postnatal lethality J:104373
short mandible J:104373
Tg(Otx1-cre)1Eag/0
Wnt3atm2Eag/Wnt3a+
Not Specified 		abnormal cerebral cortex morphology J:104373
abnormal cortical marginal zone morphology J:104373
decreased Cajal-Retzius cell number J:104373
Wnt3aem1(IMPC)Ccpcz/Wnt3a+
C57BL/6NCrl-Wnt3aem1(IMPC)Ccpcz/Ccpcz 		abnormal coat appearance J:211773
abnormal coat/ hair morphology J:211773
abnormal heart morphology J:211773
abnormal retina vasculature morphology J:211773
abnormal rib morphology J:211773
abnormal spleen morphology J:211773
abnormal vertebrae morphology J:211773
abnormal vertebral arch morphology J:211773
enlarged heart J:211773
increased circulating aspartate transaminase level J:211773
increased circulating triglyceride level J:211773
increased lymphocyte cell number J:211773
rib fusion J:211773
vertebral transformation J:211773
Wnt3astrtls/Wnt3astrtls
involves: C57BL/6 * FVB/N 		abnormal vertebrae morphology J:173681
absent hindlimb J:173681
absent tail J:173681
caudal body truncation J:173681
failure of somite differentiation J:173681
sirenomelia J:173681
Wnt3atm1(cre)Eag/Wnt3atm1(cre)Eag
Not Specified 		normal nervous system phenotype J:104373
Wnt3atm1Amc/Wnt3atm1Amc
involves: 129S1/Sv 		abnormal cervical axis morphology J:69781
abnormal cervical vertebrae morphology J:69781
abnormal somite development J:31335
cervical vertebral transformation J:69781
embryonic lethality during organogenesis, incomplete penetrance J:69781
kyphosis J:69781
sirenomelia J:69781
Wnt3atm1Amc/Wnt3atm1Amc
involves: 129S1/Sv * C57BL/6J 		abnormal gastrulation J:16716
abnormal mesoderm development J:16716
abnormal nervous system morphology J:16716
abnormal rostral-caudal axis patterning J:16716
abnormal spinal cord morphology J:16716
absent tail J:16716
absent tail bud J:16716
caudal body truncation J:16716
decreased body length J:16716
embryonic lethality during organogenesis, complete penetrance J:16716
incomplete somite formation J:16716
kinked neural tube J:16716
truncated notochord J:16716
Wnt3atm1Amc/Wnt3avt
involves: 129S1/Sv * C3H/HeJ * C57BL/6J * C57BR 		abnormal intestine morphology J:31335
abnormal somite development J:31335
abnormal thoracic vertebrae morphology J:31335
abnormal urination J:31335
absent sacral vertebrae J:31335
absent tail J:31335
decreased embryo size J:31335
decreased lumbar vertebrae number J:31335
decreased thoracic vertebrae number J:31335
hindlimb paralysis J:31335
premature death J:31335
spina bifida J:31335
Wnt3avt/Wnt3avt
B6EiC3Sn a/A-Egfrwa2 Wnt3avt/J 		cervical vertebral transformation J:69781
lumbar vertebral transformation J:69781
sacral vertebral transformation J:69781
thoracic vertebral transformation J:69781
Wnt3avt/Wnt3avt
involves: A * A/Gr * C57BR 		abnormal neural tube morphology J:14984
abnormal tail bud morphology J:14984
abnormal tail morphology J:14984
abnormal tailgut morphology J:14984
decreased ventral ectodermal ridge size J:14984
vestigial tail J:14984
Wnt3avt/Wnt3avt
involves: C3H/HeJ * C57BL/6J * C57BR 		abnormal bone ossification J:31335
abnormal caudal vertebrae morphology J:31335
abnormal somite development J:31335
decreased caudal vertebrae number J:31335
vestigial tail J:31335
Wnt3avt/Wnt3avt
involves: C57BR 		decreased caudal vertebrae number J:13062
reduced female fertility J:13062
vestigial tail J:13062
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory