Wnt4 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wnt4
wingless-type MMTV integration site family, member 4
MGI:98957

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bax^tm1Sjk/Bax^tm1Sjk Wnt4^tm1Amc/Wnt4^{tm3(EGFP/cre)Amc} involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal oogenesis	J:203797
Dkk1^tm1.1Svo/Dkk1^tm1.2Svo Wnt4^{tm2(EGFP/cre)Svo}/Wnt4⁺ involves: 129P2/OlaHsd * C57BL/6 * SJL	normal renal/urinary system phenotype	J:173125
Hnf1b^tm1Ics/Hnf1b⁺ Wnt4^{tm2(EGFP/cre)Svo}/Wnt4⁺ involves: 129P2/OlaHsd	abnormal renal tubule morphology	J:194051
	renal glomerulus cyst	J:194051
Hnf1b^tm1Ics/Hnf1b^tm1Sce Wnt4^{tm2(EGFP/cre)Svo}/Wnt4⁺ involves: 129P2/OlaHsd	abnormal kidney morphology	J:194051
	abnormal loop of Henle morphology	J:194051
	abnormal metanephros morphology	J:194051
	abnormal proximal convoluted tubule morphology	J:194051
	abnormal renal tubule morphology	J:194051
	hydronephrosis	J:194051
	postnatal lethality, complete penetrance	J:194051
	renal glomerulus cyst	J:194051
Hnf1b^tm1Sce/Hnf1b⁺ Wnt4^{tm2(EGFP/cre)Svo}/Wnt4⁺ involves: 129P2/OlaHsd	normal renal/urinary system phenotype	J:194051
Sox7^tm1.1Dsco/Sox7⁺ Wnt4^{tm2(EGFP/cre/ERT2)Amc}/Wnt4⁺ involves: 129/Sv * 129S/SvEv * C57BL/6 * C57BL/6J	atrioventricular cushion hypoplasia	J:338879
	lethality during fetal growth through weaning, incomplete penetrance	J:338879
	muscular ventricular septal defect	J:338879
	perimembraneous ventricular septal defect	J:338879
	ventricular septal defect	J:338879
Tcf21^tm2.1Seq/Tcf21^tm1Jrt Wnt4^{tm2(EGFP/cre)Svo}/Wnt4⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal podocyte morphology	J:217144
	abnormal renal glomerulus morphology	J:217144
	small kidney	J:217144
Wnt1^tm1Brd/Wnt1^tm1Brd Wnt4^tm1Amc/Wnt4^tm1Amc involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6J	decreased thymocyte number	J:75999
Wnt4^tm1Amc/Wnt4⁺ Wnt5a^tm1Amc/Wnt5a^tm1Amc involves: 129S1/Sv * 129S7/SvEvBrd	abnormal limb morphology	J:155074
	decreased motor neuron number	J:155074
Wnt4^tm1Amc/Wnt4⁺ Wnt5a^tm1Amc/Wnt5a^tm1Amc Wnt5b^tm1Tmj/Wnt5b^tm1Tmj involves: 129S1/Sv * 129S7/SvEvBrd	abnormal limb morphology	J:155074
	abnormal motor neuron morphology	J:155074
Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a⁺ involves: 129S1/Sv * 129S7/SvEvBrd	abnormal motor neuron morphology	J:155074
Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a⁺ Wnt5b^tm1Tmj/Wnt5b^tm1Tmj involves: 129S1/Sv * 129S7/SvEvBrd	abnormal limb morphology	J:155074
	abnormal motor neuron morphology	J:155074
	decreased motor neuron number	J:155074
Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a^tm1Amc involves: 129S1/Sv * 129S7/SvEvBrd	abnormal limb morphology	J:155074
	abnormal motor neuron morphology	J:155074
Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a^tm1Amc Wnt5b^tm1Tmj/Wnt5b⁺ involves: 129S1/Sv * 129S7/SvEvBrd	abnormal limb morphology	J:155074
	abnormal motor neuron morphology	J:155074
Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a^tm1Amc Wnt5b^tm1Tmj/Wnt5b^tm1Tmj involves: 129S1/Sv * 129S7/SvEvBrd	embryonic lethality, complete penetrance	J:155074
Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5b^tm1Tmj/Wnt5b^tm1Tmj involves: 129S1/Sv * 129S7/SvEvBrd	abnormal motor neuron morphology	J:155074
	decreased motor neuron number	J:155074

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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