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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Wnt5a
wingless-type MMTV integration site family, member 5A
MGI:98958
92 phenotypes from 5 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal embryo attachment J:233595
abnormal embryo development J:233595
abnormal maternal decidual layer morphology J:233595
abnormal placenta morphology J:233595
abnormal trophoblast giant cell proliferation J:233595
abnormal uterine-embryonic axis J:233595
abnormal uterus morphology J:233595
decreased litter size J:233595
decreased placental labyrinth size J:233595
impaired embryo implantation J:233595
impaired spacing of implantation sites J:233595
reduced female fertility J:233595
normal reproductive system phenotype J:233595
twin decidual capsule J:233595
Pgrtm2(cre)Lyd/Pgr+
Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
involves: 129S1/Sv * 129X1/SvJ 		abnormal embryo attachment J:233595
abnormal embryo development J:233595
abnormal maternal decidual layer morphology J:233595
abnormal placenta morphology J:233595
abnormal trophoblast giant cell proliferation J:233595
abnormal uterine-embryonic axis J:233595
abnormal uterus morphology J:233595
decreased litter size J:233595
decreased placental labyrinth size J:233595
impaired embryo implantation J:233595
impaired spacing of implantation sites J:233595
reduced female fertility J:233595
normal reproductive system phenotype J:233595
twin decidual capsule J:233595
Wnt5ab2b3077.1Clo/Wnt5ab2b3077.1Clo
C57BL/6J-Wnt5ab2b3077.1Clo 		abnormal autopod morphology J:175213
abnormal intestine morphology J:175213
abnormal kidney morphology J:175213
abnormal limb morphology J:175213
abnormal tail morphology J:175213
abnormal thoracic cavity morphology J:175213
atrioventricular septal defect J:175213
cleft palate J:175213
cleft upper lip J:175213
double outlet right ventricle J:175213
heart left ventricle hypoplasia J:175213
micrognathia J:175213
persistent truncus arteriosus J:175213
pulmonary artery hypoplasia J:175213
pulmonary hypoplasia J:175213
short snout J:175213
syndactyly J:175213
thymus hypoplasia J:175213
Wnt5atm1.1Krvl/Wnt5atm1.1Krvl
involves: 129S6/SvEvTac * C57BL/6 		no abnormal phenotype detected J:196291
Wnt5atm1.1Krvl/Wnt5atm1.1Krvl
Tg(Th-cre)#Gsat/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N 		abnormal superior cervical ganglion morphology J:196291
abnormal sympathetic neuron innervation pattern J:196291
decreased neuron number J:196291
Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
involves: 129S/SvEv * 129S1/Sv * C57BL/6 		abnormal intestine regeneration J:187747
abnormal wound healing J:187747
Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S1/Sv * C57BL/6 * CBA 		abnormal intestine regeneration J:187747
abnormal wound healing J:187747
Wnt5atm1Amc/Wnt5atm1.1Krvl
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * CBA/J 		abnormal axon extension J:196291
abnormal craniofacial morphology J:196291
abnormal sympathetic neuron innervation pattern J:196291
increased neuron apoptosis J:196291
neonatal lethality, complete penetrance J:196291
Wnt5atm1Amc/Wnt5atm1Amc
involves: 129S7/SvEvBrd 		abnormal anus morphology J:153152
abnormal colon morphology J:153152
abnormal liver morphology J:153152
abnormal primordial germ cell migration J:179805
abnormal rectum morphology J:153152
abnormal urinary bladder morphology J:153152
absent anus J:153152
absent rectum J:153152
anal atresia J:153152
decreased autopod size J:184918
decreased body size J:153152
decreased colon length J:153152
decreased primordial germ cell number J:179805
enlarged liver J:153152
genital tubercle hypoplasia J:153152
increased primordial germ cell apoptosis J:179805
normal nervous system phenotype J:155074
short limbs J:153152, J:184918
short tail J:153152
Wnt5atm1Amc/Wnt5atm1Amc
involves: 129S7/SvEvBrd * C57BL/6 		abnormal digestive system development J:204986
abnormal embryonic tissue morphology J:52600
abnormal lung development J:78384
abnormal lung interstitium morphology J:78384
abnormal mesenchyme morphology J:204986
abnormal midgut morphology J:204986
abnormal presomitic mesoderm morphology J:52600
abnormal primitive streak formation J:52600
abnormal reproductive system morphology J:52600
abnormal vertebrae morphology J:52600
absent caudal vertebrae J:52600
absent external female genitalia J:52600
absent external male genitalia J:52600
adactyly J:52600
decreased body length J:52600
decreased somite size J:52600
decreased tongue size J:52600
decreased tracheal cartilage ring number J:78384
delayed bone ossification J:52600
neonatal lethality, complete penetrance J:52600, J:78384
respiratory failure J:78384
rib fusion J:52600
short humerus J:52600
short limbs J:52600
short mandible J:52600
short radius J:52600
short snout J:52600
short trachea J:78384
short ulna J:52600
short vertebral column J:78384
small ears J:52600
small vertebrae J:52600
vertebral fusion J:52600
vestigial tail J:52600
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory