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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Yaa
accelerated autoimmunity and lymphoproliferation transposition
MGI:99140
30 phenotypes from 1 allele in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
X/Yaa
(C57BL/6J x BXSB)F1 		enlarged lymph nodes J:6235
increased susceptibility to autoimmune disorder J:6235
premature death J:6235
X/Yaa
(NZB x B6.SB/Le-Yaa)F1 		increased monocyte cell number J:129409
X/Yaa
(NZB x BXSB)F1 		abnormal immune cell physiology J:6235
abnormal lymph node morphology J:6235
decreased erythrocyte cell number J:6235
enlarged lymph nodes J:6235
increased anti-erythrocyte antigen antibody level J:6235
increased anti-nuclear antigen antibody level J:6235
increased autoantibody level J:6235
increased spleen weight J:6235
increased susceptibility to autoimmune disorder J:6235
porphyria J:6235
premature death J:6235
X/Yaa
(NZW x BXSB)F1 		abnormal immune serum protein physiology J:7276
increased susceptibility to autoimmune disorder J:7276
premature death J:7276
X/Yaa
(NZW x SB)F1 		abnormal immune serum protein physiology J:7276
glomerulonephritis J:7276
increased susceptibility to autoimmune disorder J:7276
premature death J:7276
X/Yaa
(SJL/J x BXSB)F1 		enlarged lymph nodes J:6235
increased susceptibility to autoimmune disorder J:6235
premature death J:6235
X/Yaa
B6.SB-Yaa/J 		decreased marginal zone B cell number J:127600
increased splenocyte proliferation J:127600
X/Yaa
BXSB/MpJ 		abnormal B cell differentiation J:108760
abnormal lymph node morphology J:6235
abnormal spleen B cell follicle morphology J:179430
abnormal T cell subpopulation ratio J:179430
decreased erythrocyte cell number J:6235
enlarged lymph nodes J:6235
glomerulonephritis J:6235
increased anti-erythrocyte antigen antibody level J:6235
increased anti-nuclear antigen antibody level J:179430
increased circulating interleukin-21 level J:93740
increased IgG1 level J:93740, J:179430
increased IgG2a level J:179430
increased IgG2b level J:179430
increased IgG3 level J:93740
increased monocyte cell number J:7308
increased plasma cell number J:108760
increased spleen weight J:6235
increased splenocyte number J:179430
increased susceptibility to autoimmune disorder J:6235, J:108760
increased urine protein level J:7308
premature death J:6235, J:7308
renal glomerular immunoglobulin deposits J:179430
X/Yaa
BXSB/MpJScr 		decreased CD4-positive, alpha-beta T cell number J:10973
glomerulonephritis J:10973
increased anti-nuclear antigen antibody level J:10973
increased IgG level J:10973
increased monocyte cell number J:10973
increased susceptibility to autoimmune disorder J:10973
premature death J:10973
X/Yaa
involves: BXSB * NZB 		enlarged lymph nodes J:6235
increased susceptibility to autoimmune disorder J:6235
premature death J:6235
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory