Ybx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ybx1
Y box protein 1
MGI:99146

27 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ybx1^{Gt(W094B04)Wrst}/Ybx1⁺ chimera involves: 129S2/SvPas	embryonic lethality, complete penetrance	J:152136
Ybx1^tm1Ley/Ybx1^tm1Ley either: 129X1/SvJ-Ybx1^tm1Ley or (involves: 129X1/SvJ * C57BL/6)	abnormal craniofacial morphology	J:99099
	abnormal neural tube closure	J:99099
	abnormal redox activity	J:99099
	cyanosis	J:99099
	decreased embryo size	J:99099
	decreased fibroblast proliferation	J:99099
	early cellular replicative senescence	J:99099
	exencephaly	J:99099
	intracerebral hemorrhage	J:99099
	lethality throughout fetal growth and development, incomplete penetrance	J:99099
	liver hypoplasia	J:99099
	neonatal lethality, complete penetrance	J:99099
	pallor	J:99099
	respiratory failure	J:99099
Ybx1^tm1Ley/Ybx1^tm1Ley involves: 129X1/SvJ * C57BL/6	decreased embryo size	J:115970
	decreased fetal size	J:115970
	exencephaly	J:115970
	lethality during fetal growth through weaning, complete penetrance	J:115970
Ybx1^tm1Tuch/Ybx1^tm1Tuch involves: 129S/SvEv * C57BL/6	abnormal brain development	J:117725
	abnormal cell morphology	J:117725
	abnormal definitive hematopoiesis	J:117725
	abnormal mandible morphology	J:117725
	abnormal maxilla morphology	J:117725
	decreased fibroblast proliferation	J:117725
	edema	J:117725
	embryonic growth retardation	J:117725
	exencephaly	J:117725
	incomplete rostral neuropore closure	J:117725
	lethality throughout fetal growth and development, complete penetrance	J:117725
	small liver	J:117725

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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