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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zfp36
zinc finger protein 36
MGI:99180
53 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Zfp36tm1(KOMP)Vlcg/Zfp36+
C57BL/6N-Zfp36tm1(KOMP)Vlcg/Nju 		decreased mean corpuscular volume J:211773
increased fasting circulating glucose level J:211773
increased leukocyte cell number J:211773
Zfp36tm1Pjb/Zfp36tm1Pjb
B6.Cg-Zfp36tm1Pjb 		abnormal macrophage physiology J:88443
abnormal nitric oxide homeostasis J:214114
abnormal vasodilation J:214114
autoimmune arthritis J:88443
blood vessel inflammation J:214114
decreased lymphocyte cell number J:214114
decreased systemic arterial blood pressure J:214114
normal homeostasis/metabolism phenotype J:214114
increased cellular sensitivity to oxidative stress J:214114
increased granulocyte number J:214114
increased monocyte cell number J:214114
increased neutrophil cell number J:214114
oxidative stress J:214114
thrombocytosis J:214114
Zfp36tm1Pjb/Zfp36tm1Pjb
Not Specified 		abnormal renal glomerulus morphology J:33986
abnormal thymus cortex morphology J:33986
abnormal thymus medulla morphology J:33986
absent subcutaneous adipose tissue J:33986
alopecia J:33986
autoimmune arthritis J:33986
conjunctivitis J:33986
decreased body weight J:33986
dermatitis J:33986
enlarged lymph nodes J:33986
enlarged spleen J:33986
extramedullary hematopoiesis J:33986
heart inflammation J:33986
increased leukocyte cell number J:33986
liver inflammation J:33986
postnatal growth retardation J:33986
premature death J:33986
spleen hyperplasia J:33986
thymus hypoplasia J:33986
Zfp36tm2.1Pjb/Zfp36tm2.1Pjb
involves: C57BL/6 		decreased inflammatory response J:229078
decreased susceptibility to experimental autoimmune encephalomyelitis J:229078
decreased susceptibility to induced arthritis J:229078
Zfp36tm4.1Pjb/Zfp36tm4.1Pjb
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N 		abnormal myocardium layer morphology J:188677
abnormal pilomotor reflex J:188677
abnormal renal glomerulus morphology J:188677
abnormal small intestine morphology J:188677
alveolitis J:188677
autoimmune arthritis J:188677
decreased body temperature J:188677
decreased body weight J:188677
enlarged lymph nodes J:188677
enlarged spleen J:188677
focal hepatic necrosis J:188677
increased blood urea nitrogen level J:188677
increased circulating alanine transaminase level J:188677
increased circulating lactate dehydrogenase level J:188677
increased circulating tumor necrosis factor level J:188677
increased inflammatory response J:188677
increased spleen weight J:188677
increased susceptibility to endotoxin shock J:188677
lethargy J:188677
normal mortality/aging J:188677
tachypnea J:188677
Zfp36tm4.2Pjb/Zfp36tm4.2Pjb
C57BL/6-Zfp36tm4.2Pjb 		decreased body weight J:188677
premature death J:188677
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory