Ddr1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddr1
discoidin domain receptor family, member 1
MGI:99216

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ddr1^{tm1b(EUCOMM)Hmgu}/Ddr1⁺ C57BL/6N-Ddr1^{tm1b(EUCOMM)Hmgu}/Orl	hyperactivity	J:211773
Ddr1^{tm1b(EUCOMM)Hmgu}/Ddr1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Ddr1^{tm1b(EUCOMM)Hmgu}/Orl	preweaning lethality, incomplete penetrance	J:211773
Ddr1^tm1Lex/Ddr1^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal aorta collagen fibril morphology	J:234902
	decreased anxiety-related response	J:82809
	increased locomotor activity	J:82809
Ddr1^tm1Wfv/Ddr1^tm1Wfv either: (involves: (129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal bone mineralization	J:68368
	abnormal lactation	J:68368
	abnormal mammary gland development	J:68368
	abnormal mammary gland duct morphology	J:68368
	abnormal outer ear morphology	J:68368
	failure of embryo implantation	J:68368
	increased mammary gland epithelial cell proliferation	J:68368
	postnatal growth retardation	J:68368
Ddr1^tm1Wfv/Ddr1^tm1Wfv involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cranium morphology	J:123719
Ddr1^tm1Wfv/Ddr1^tm1Wfv involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal podocyte slit diaphragm morphology	J:101769
	abnormal renal tubule epithelium morphology	J:101769
	erythrocyturia	J:101769
	normal homeostasis/metabolism phenotype	J:101769
	increased renal glomerulus basement membrane thickness	J:101769
	increased urine protein level	J:101769
	normal renal/urinary system phenotype	J:101769

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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