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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Etv2
ets variant 2
MGI:99253
44 phenotypes from 6 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Etv2Gt(141.1H7)Cmhd/Etv2Gt(141.1H7)Cmhd
involves: 129S1/Sv * 129X1/SvJ 		abnormal dorsal aorta morphology J:143866
abnormal embryonic tissue morphology J:143866
abnormal heart development J:143866
abnormal vascular development J:143866
absent heartbeat J:143866
embryonic growth retardation J:143866
embryonic lethality during organogenesis, complete penetrance J:143866
Etv2tm1Dlim/Etv2+
Not Specified 		decreased hematopoietic stem cell number J:172687
Etv2tm1Dlim/Etv2tm1Dlim
involves: C57BL/6 		abnormal blood vessel morphology J:155850
abnormal embryonic erythropoiesis J:155850
abnormal placenta development J:155850
abnormal placenta labyrinth morphology J:155850
abnormal placental labyrinth vasculature morphology J:155850
absent visceral yolk sac blood islands J:155850
absent vitelline blood vessels J:155850
normal cardiovascular system phenotype J:155850
decreased embryo size J:155850
embryonic growth retardation J:155850
embryonic lethality during organogenesis, complete penetrance J:155850
increased embryonic tissue cell apoptosis J:155850
pale yolk sac J:155850
Etv2tm1Dlim/Etv2tm2.1Dlim
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJaeSor * C57BL/6 * CBA 		abnormal hematopoietic stem cell physiology J:172687
abnormal myeloblast morphology/development J:172687
decreased bone marrow cell number J:172687
decreased hematopoietic stem cell number J:172687
decreased leukocyte cell number J:172687
impaired myelopoiesis J:172687
spleen hypoplasia J:172687
Etv2tm1Vkou/Etv2tm1Vkou
Tg(Pgk1-cre)1Lni/0
involves: BALB/c * C57BL/6 		absent erythrocytes J:194572
absent erythroid progenitor cell J:194572
embryonic growth retardation J:194572
embryonic lethality during organogenesis, complete penetrance J:194572
Etv2tm1Vkou/Etv2tm1Vkou
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * SJL 		no abnormal phenotype detected J:194572
Etv2tm2.1Dlim/Etv2tm2.1Dlim
involves: 129S4/SvJaeSor * C57BL/6 		no abnormal phenotype detected J:172687
Etv2tm2.1Nshk/Etv2tm2.1Nshk
Tg(Pdgfra-cre/ERT2)1Wdr/0
involves: C57BL/6NCrlj * CBA/JNCrlj 		abnormal angiogenesis J:193389
abnormal vitelline vasculature morphology J:193389
decreased hematopoietic cell number J:193389
decreased vascular endothelial cell number J:193389
Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata/Gt(ROSA)26Sor+
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: C57BL/6NCrlj * C57BL/10 * CBA/Ca * CBA/JNCrlj 		abnormal bone marrow cell morphology/development J:203163
abnormal hematopoietic system morphology/development J:203163
anemia J:203163
decreased common myeloid progenitor cell number J:203163
decreased erythroid progenitor cell number J:203163
preweaning lethality, incomplete penetrance J:203163
Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata/Gt(ROSA)26Sor+
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL 		abnormal definitive hematopoiesis J:203163
abnormal vitelline vasculature morphology J:203163
embryonic lethality during organogenesis, incomplete penetrance J:203163
hemorrhage J:203163
Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata/Gt(ROSA)26Sor+
Meox1tm1(cre)Jpa/Meox1+
involves: C57BL/6NCrlj * CBA/JNCrlj 		no abnormal phenotype detected J:203163
Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata/Gt(ROSA)26Sor+
Sox1tm1(cre)Take/Sox1+
involves: C57BL/6NCrlj * CBA/JNCrlj 		normal cardiovascular system phenotype J:203163
normal embryo phenotype J:203163
normal hematopoietic system phenotype J:203163
normal mortality/aging J:203163
Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata/Gt(ROSA)26Sor+
Sox17tm1(icre)Heli/Sox17+
involves: 129S2/SvPas * C57BL/6NCrlj * CBA/JNCrlj 		normal embryo phenotype J:203163
normal mortality/aging J:203163
Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata/Gt(ROSA)26Sortm1(CAG-Etv2,-GFP)Hkata
involves: C57BL/6NCrlj * CBA/JNCrlj 		no abnormal phenotype detected J:203163
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory