Ptgds Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptgds
prostaglandin D2 synthase (brain)
MGI:99261

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ano3^tm1.1Lyj/Ano3^tm1.1Lyj Ptgds^{tm1.1(cre)Gvn}/Ptgds⁺ involves: 129X1/SvJ * C57BL/6 * FVB/N	abnormal body temperature homeostasis	J:310618
	environmentally induced seizures	J:310618
Apc^Min/Apc⁺ Ptgds^tm1Ohy/Ptgds^tm1Ohy involves: 129P2/OlaHsd * C57BL/6J	increased intestinal adenoma incidence	J:118232
Cdkn2a^tm1.1Brn/Cdkn2a^tm1.1Brn Nf2^tm2Gth/Nf2^tm2Gth Ptgds^{tm1.1(cre)Gvn}/Ptgds⁺ involves: 129P2/OlaHsd * FVB/N	increased meningioma incidence	J:173718
	normal mortality/aging	J:173718
	normal neoplasm	J:173718
Nf2^tm2Gth/Nf2^tm2Gth Ptgds^{tm1.1(cre)Gvn}/Ptgds⁺ involves: 129P2/OlaHsd * FVB/N	increased meningioma incidence	J:173718
	increased osteoma incidence	J:173718
	increased pituitary adenoma incidence	J:173718
	normal mortality/aging	J:173718
Nf2^tm2Gth/Nf2^tm2Gth Ptgds^{tm1.1(cre)Gvn}/Ptgds⁺ Trp53^tm1Brn/Trp53^tm1Brn involves: 129P2/OlaHsd * FVB/N	increased nervous system tumor incidence	J:173718
	increased osteosarcoma incidence	J:173718
	premature death	J:173718

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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