Hira Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hira
histone cell cycle regulator
MGI:99430

48 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hira^{tm1a(EUCOMM)Wtsi}/Hira⁺ C57BL/6N-Hira^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased leukocyte cell number	J:175295
	decreased rib number	J:175295
Hira^tm1Pjs/Hira^tm1Pjs involves: 129S1/Sv * C57BL/6	abnormal axial mesoderm morphology	J:75491
	abnormal brain development	J:75491
	abnormal developmental patterning	J:75491
	abnormal embryo turning	J:75491
	abnormal embryonic neuroepithelium morphology	J:75491
	abnormal embryonic tissue morphology	J:75491
	abnormal head mesenchyme morphology	J:75491
	abnormal head morphology	J:75491
	abnormal heart development	J:75491
	abnormal heart morphology	J:75491
	abnormal hindbrain development	J:75491
	abnormal left-right axis patterning	J:75491
	abnormal mesendoderm development	J:75491
	abnormal midbrain-hindbrain boundary development	J:75491
	abnormal neural plate morphology	J:75491
	abnormal neural tube morphology	J:75491
	abnormal notochord morphology	J:75491
	abnormal pharyngeal arch morphology	J:75491
	abnormal prechordal plate morphology	J:75491
	abnormal primitive streak morphology	J:75491
	abnormal somite shape	J:75491
	decreased embryo size	J:75491
	decreased somite size	J:75491
	embryonic growth arrest	J:75491
	embryonic growth retardation	J:75491
	embryonic lethality during organogenesis, complete penetrance	J:75491
	embryonic-extraembryonic boundary constriction	J:75491
	enlarged allantois	J:75491
	failure of chorioallantoic fusion	J:75491
	failure to gastrulate	J:75491
	incomplete somite formation	J:75491
	kinked neural tube	J:75491
	open neural tube	J:75491
Hira^tm1Pjs/Hira^tm1Pjs involves: 129S1/Sv * C57BL/6 * CD-1	abnormal allantois morphology	J:75491
	abnormal blood vessel morphology	J:75491
	abnormal brain development	J:75491
	abnormal embryo development	J:75491
	abnormal embryo turning	J:75491
	abnormal forebrain morphology	J:75491
	abnormal head morphology	J:75491
	abnormal heart development	J:75491
	abnormal heart tube morphology	J:75491
	abnormal paraxial mesoderm morphology	J:75491
	abnormal rostral-caudal axis patterning	J:75491
	abnormal somite shape	J:75491
	abnormal vitelline vasculature morphology	J:75491
	caudal body truncation	J:75491
	decreased somite size	J:75491
	normal embryo phenotype	J:75491
	embryonic growth retardation	J:75491
	embryonic lethality during organogenesis, complete penetrance	J:75491
	failure of heart looping	J:75491
	failure to gastrulate	J:75491
	irregular heartbeat	J:75491
	pericardial edema	J:75491
Hira^tm2Pjs/Hira^tm2Pjs involves: 129S6/SvEvTac * C57BL/6	abnormal embryo development	J:75491
Hira^tm2Pjs/Hira^tm2Pjs involves: 129S6/SvEvTac * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:75491
Hira^{Tn(mm-DTT-3XSstop)L.1Ddra}/Hira^{Tn(mm-DTT-3XSstop)L.1Ddra} involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N	abnormal embryo development	J:156413
	embryonic lethality during organogenesis, complete penetrance	J:156413

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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