Mc1r Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mc1r
melanocortin 1 receptor
MGI:99456

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
A/A Mc1r^E-tob/Mc1r⁺ M. m. domesticus poschiavinus	abnormal coat/hair pigmentation	J:22593
A/A Mc1r^E-tob/Mc1r⁺ M. m. domesticus poschiavinus	darkened coat color	J:22593
A/A Mc1r^E-tob/Mc1r^E-tob M. m. domesticus poschiavinus	abnormal coat/hair pigmentation	J:22593
A/A Mc1r^E-tob/Mc1r^E-tob M. m. domesticus poschiavinus	darkened coat color	J:22593
a/A Mc1r^e/Mc1r^e Pomc^tm1Sora/Pomc^tm1Sora Tg(MC1R)1Jkn/? involves: 129S6/SvEvTac * C57BL/6Ha	abnormal hair follicle pheomelanosome pheomelanin content	J:129904
	yellow coat color	J:129904
a/a Mc1r^e/Mc1r^e Pomc^tm1Sora/Pomc^tm1Sora Tg(MC1R)1Jkn/? involves: 129S6/SvEvTac * C57BL/6Ha	abnormal hair follicle pheomelanosome pheomelanin content	J:129904
	yellow coat color	J:129904
A^y-Jkn/A Mc1r^e/Mc1r^e involves: C57BL/6Ha * C57BL/6N	yellow coat color	J:129904
A^y-Jkn/A Mc1r^e/Mc1r^e Tg(MC1R)1Jkn/0 involves: C57BL/6Ha * C57BL/6N	yellow coat color	J:129904
Adamts20^bt/Adamts20^bt Mc1r^e/Mc1r^e involves: C57BL/6Ha * DBA/2J	belted	J:5110
	yellow coat color	J:5110
Ednrb^s/Ednrb^s Mc1r^e/Mc1r^e Not Specified	white spotting	J:5110
Ednrb^s/Ednrb^s Mc1r^e/Mc1r^e Not Specified	yellow coat color	J:5110
Mc1r^e/Mc1r^e Mlph^ln/Mlph^ln Not Specified	diluted coat color	J:5110
Mc1r^e/Mc1r^e Pepd^dal/Pepd^dal involves: C57BL/6J * CBA/J	decreased body size	J:143333
Mc1r^e/Mc1r^e Pepd^dal/Pepd^dal involves: C57BL/6J * CBA/J	yellow coat color	J:143333
Mc1r^e/Mc1r^e Tg(KRT14-Kitl)1Takk/0 involves: C57BL/6 * SJL	abnormal melanogenesis	J:112959
Mc1r^e/Mc1r^e Xpc^tm1Brd/Xpc^tm1Brd Tg(KRT14-Kitl)1Takk/0 involves: 129S7/SvEvBrd * C57BL/6 * SJL	increased squamous cell carcinoma incidence	J:112959
	increased tumor incidence	J:112959
	skin lesions	J:112959
	thick epidermis	J:112959
	weight loss	J:112959
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(KRT14-rtTA)F42Efu/0 Tg(tetO-EDN1,-lacZ)9Mhus/0 Tg(Tyr-cre/ERT2)13Bos/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB	abnormal epidermal melanocyte morphology	J:231435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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